Results 131 to 140 of about 2,538,192 (355)

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Assessing the association between triglyceride-glucose index and atrial fibrillation: a systematic review and meta-analysis

European Journal of Medical Research
Background An essential relationship between insulin resistance (IR) and atrial fibrillation (AF) has been demonstrated. Among the methods used to assess IR, the triglyceride-glucose (TyG) index is the more straightforward, dimensionless, and low-cost ...
Alireza Azarboo, Amir Hossein Behnoush, Zahra Vaziri, Mohammad Shahabaddin Daneshvar, Aryan Taghvaei, Arash Jalali, Alessandro Cannavo, Amirmohammad Khalaji   +7 more
doaj   +1 more source

Heart failure with preserved ejection fraction and non‐alcoholic fatty liver disease: new insights from bioinformatics

, 2022
Anzhu Wang, Qiang Li, Zhuo Sun, Yifei Wang, Shuangqing Fu, Dawu Zhang, Xiaochang Ma   +6 more
openalex   +1 more source

Lifestyle Intervention in Chronic Ischaemic Heart Disease and Type 2 Diabetes (the LeIKD study): study protocol of a prospective, multicentre, randomised, controlled trial [PDF]

, 2021
Pia von Korn, Hanna Sydow, Stefan Neubauer, André Duvinage, Anja Mocek, Sophia Dinges, Bjoern Hackenberg, Mario Weichenberger, Julia Schoenfeld, Volker Eric Amelung, Stephan Mueller, Martin Halle   +11 more
openalex   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source

Antithrombotic therapy in adults with ectatic coronary artery disease: a systematic review and network meta-analysis

The Egyptian Heart Journal
Background Many studies have validated the use of antiplatelet or anticoagulant therapy in coronary artery ectasia (CAE) to reduce major adverse cardiovascular events (MACE); however, it is not completely known which group of these antithrombotic ...
Alireza Azarboo, Mohammad Shahabaddin Daneshvar, Alireza Sattari Abroy, Ramin Assempoor, Aryan Taghvaei, Ali Nasrollahizadeh, Mohsen Hajiqasemi, Amirhossein Ghaseminejad-Raeini, Kaveh Hosseini   +8 more
doaj   +1 more source

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey, Jennifer M. Farmer, David R. Lynch   +2 more
wiley   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Individual Atrasentan Exposure is Associated With Long‐term Kidney and Heart Failure Outcomes in Patients With Type 2 Diabetes and Chronic Kidney Disease [PDF]

, 2020
Jeroen V. Koomen, Jasper Stevens, George L. Bakris, Ricardo Correa‐Rotter, Fan Fan Hou, Dalane W. Kitzman, Donald E. Kohan, Hirofumi Makino, John J.V. McMurray, Hans‐Henrik Parving, Vlado Perkovic, Sheldon W. Tobe, Dick de Zeeuw, Hiddo J.L. Heerspink   +13 more
openalex   +1 more source