Results 111 to 120 of about 1,425,667 (309)
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
EFFICACY AND SAFETY OF TRANSRADIAL APPROACH IN PRIMARY PCI FOR STEMI
Pakistan Armed Forces Medical Journal, 2022 Objective: To determine the efficacy and safety of transradial approach in primary percutanous intervention in acute ST segment elevation myocardial infarction.
Ayaz Ahmad +5 more
doaj
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2015 Objective: The purpose of study was to determine whether thrombolysis in myocardial infarction (TIMI) risk score applied to patients undergoing primary percutaneous coronary intervention identifies a group of patients at high risk for adverse outcome.
Abdul Hameed Siddiqui +9 more
doaj +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
CDC's National Center for Chronic Disease Prevention and Health Promotion Division of Heart Disease and Stroke Prevention at a glance [PDF]
CDC\u2019s Division for Heart Disease and Stroke Prevention supports state, local, tribal, and territorial heart disease and stroke prevention programs that help millions of Americans control their high blood pressure and reduce other risk factors for ...
core
DIFFERENCE IN MORTALITY BETWEEN ACUTE STEMI PATIENTS TREATED WITH THROMBOLYSIS AND PRIMARY PCI
Pakistan Armed Forces Medical Journal, 2015 Objective: To compare the difference in mortality between acute ST elevation myocardial infarction (STEMI) patients treated with thrombolysis and primary percutaneous coronary intervention (PCI) at the Armed Forces Institute of Cardiology, Rawalpindi.
Qurban Khan +6 more
doaj +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
INFLUENCE OF MACRONUTRITIENTS INTAKE ON NITROGEN BALANCE IN CRITICALLY ILL PATIENTS
Pakistan Armed Forces Medical Journal, 2020 Objective: To assess the frequency of positive nitrogen balance in cardiac surgical intensive care unit and correlating with critical illness and to find out the relationship between carbohydrates, protein and fat intake and nitrogen balance.
Safdar Ali Khan +5 more
doaj
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source