Results 131 to 140 of about 4,967,645 (304)

PILOT SURVEY OF PATIENT SATISFACTION TOWARDS OUTPATIENT SERVICES AT A TERTIARY CARDIAC CARE HOSPITAL

Pakistan Armed Forces Medical Journal, 2020
Objective: To evaluate patient satisfaction in an outpatient department services of a tertiary cardiac care hospital. Study Design: Descriptive cross-sectional study. Place and Duration of study: Outpatient department of AFIC&NIHD Rawalpindi Pakistan
Farrah Pervaiz, Sabeen Khurshid Zaidi, Shahab Naqvi, Aysha Siddiqa, Hafsa Khalil, Asmat Abbas Shah   +5 more
doaj  

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Cardiac parasympathetic denervation reduces hypoxic tachycardia, baroreflex sensitivity and heart rate variability in humans

Scientific Reports
The autonomic regulation of heart rate (HR) reactivity to acute hypoxia remains unclear. Parasympathetic cardioneuroablation (PCNA) may serve as a novel model for the analysis of physiological consequences of reduced vagal influence over sinus node in ...
Piotr Niewinski, Stanislaw Tubek, Krystian Josiak, Krzysztof Nowak, Piotr Ponikowski   +4 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Decoding the liver-heart axis in cardiometabolic diseases

The liver and heart are closely interconnected organs, and their bidirectional interaction plays a central role in cardiometabolic disease. In this review, we summarize current evidence linking liver dysfunction—particularly metabolic dysfunction ...
Vidal-Puig, Antonio, Schiattarella, Gabriele G, Vacca, A., Strocchi, S., Kaminska, Dorota, Capone, F., Vidal-Puig, A., Greco, C.M., Lusis, Aldons J, Bidault, G., Sarver, D., Vacca, Antonio, Lusis, A.J., Schiattarella, G.G., Greco, Carolina M, Kaminska, D., Sarver, Dylan, Bidault, Guillaume, Capone, Federico, Strocchi, Stefano, Schiattarella, Gabriele G., Greco, Carolina M., Lusis, Aldons J.   +22 more
core   +1 more source

PERCUTANEOUS CORONARY INTERVENTION FOR CHRONIC TOTAL OCCLUSION: EXPERIENCE AT ARMED FORCES INSTITUTE OF CARDIOLOGY

Pakistan Armed Forces Medical Journal, 2015
Objective: To evaluate the procedural outcome of patients having Chronic Total Occlusion (CTO) undergoing Percutaneous Coronary Intervention (PCI) at our clinical setup. Study Design: Descriptive cross sectional study. Place and Duration of Study:
Zahoor Aslam Khattak, Nadir Khan, Muhammad Qaiser Khan, Naseer Ahmed Samore, Adeel ., Sohail Aziz   +5 more
doaj  

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source