Results 91 to 100 of about 4,967,645 (304)
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
50 years of heart disease in Ireland: mortality, morbidity and health services implications.
, 2000 In 1999, 12,996 people died from vascular diseases in Ireland. In 1950, 11,887 people died from the same group of diseases. The populations of the respective years differed, of course (approximately 4 million vs 2.9 million), and a higher proportion ...
Codd, Mary B. +3 more
core
PM348 Heart education assessment and rehabilitation toolkit: Heart online. A web resource for clinicians [PDF]
, 2014 Access to the right information at the right time is a challenge facing health professionals across the globe. HEART Online (www.heartonline.org.au) is a website designed to support the delivery of evidence based care for the prevention and ...
Hickey, Annabel +4 more
core +1 more source
Pakistan Armed Forces Medical Journal, 2015 Objective: To determine in hospital clinical outcome of primary PCI in elderly patients. Study Design: Descriptive cross-sectional study. Place and Duration of Study: This study was performed in Armed Force Institute of Cardiology from November ...
Imran Ghani +7 more
doaj +2 more sources
Pakistan Armed Forces Medical Journal, 2014 Objective: To determine the procedural outcome of primary percutaneous coronary interventions (PCI) in ST segment elevation myocardial infarction. Study Design: A quasi-experimental study.
Naseer Ahmad Samore +7 more
doaj +2 more sources
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2014 Objective: The aim of this study was to report management; peri-procedural and short term results of patients hospitalized with acute myocardial infarction (MI)complicated by ventricular septal rupture (VSR) considered high risk or unfit for surgical ...
Abdul Hameed Siddiqui +7 more
doaj +2 more sources
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source