Results 91 to 100 of about 2,421,555 (309)

Diabetic Heart Disease

British Journal of Multidisciplinary and Advanced Studies, 2020
Changes in the human environment, behavior, and lifestyle are contributing to the upsurge in the incidence of diabetes. However, better management has resulted in a longer survival of patients with diabetes, but it is accompanied by long-term chronic complications due to hyperglycemia. Individuals with diabetes most often die of cardiovascular disease (
P Ram Mohan Reddy, R Vinola, T Samyuktha, D Sujin, S Saran Kumar, D Hepcy Kalarani   +5 more
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Morbidity profiles of Kerala and all-India: An Economic perspective [PDF]

This study examines the economic profiles of morbidity by disease in Kerala and all-India by estimating Engel elasticities for diseases and classifying them as between those associated with affluence and deprivation. Morbidity rates, in general, are more
M. H. Suryanarayana
core  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Females and Exercise Capacity Impairment in Heart Failure: A Sex-Focused Analysis

Journal of Cardiovascular Development and Disease
Heart failure (HF) is becoming increasingly common, especially in older females, and displays marked sex-related differences in pathophysiology, treatment, and outcomes. Submaximal exercise capacity (SEC), frequently measured by the six-minute walk test (
Ainhoa Lorenzo, Raúl Ramos-Polo, Laia Lorenzo-Esteller, Xinying Lin, Emma Barragan, Paula Aranda, Èlia Boixader, Foix Regull, Nerea Martín, Ariana Ollé, Marc Llagostera, Núria José-Bazán, Pedro Moliner, Cristina Enjuanes, Josep Comin-Colet   +14 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Lateral costal artery as a culprit for the steal phenomenon after coronary artery bypass grafting: a case report and review of the literature

Journal of Cardiothoracic Surgery
Background The left internal thoracic artery (LITA) has been widely accepted as the standard for revascularizing the left anterior descending artery during coronary artery bypass grafting (CABG) surgery.
Michal Trebišovský, Marián Homola, Adrián Kolesár, Štefan Lukačin, Anton Bereš   +4 more
doaj   +1 more source

Strengths and limitations of HFpEF probability scores in the era of precision medicine

Frontiers in Medicine
BackgroundHeart failure with preserved ejection fraction is a heterogeneous syndrome influenced by comorbidities, complicating diagnosis and treatment.
Michał Wilk, Tomasz Kotwica, Robert Zymliński, Piotr Gajewski   +3 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Cardiac parasympathetic denervation reduces hypoxic tachycardia, baroreflex sensitivity and heart rate variability in humans

Scientific Reports
The autonomic regulation of heart rate (HR) reactivity to acute hypoxia remains unclear. Parasympathetic cardioneuroablation (PCNA) may serve as a novel model for the analysis of physiological consequences of reduced vagal influence over sinus node in ...
Piotr Niewinski, Stanislaw Tubek, Krystian Josiak, Krzysztof Nowak, Piotr Ponikowski   +4 more
doaj   +1 more source