Results 91 to 100 of about 1,419,649 (316)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

A novel three-dimensional echocardiographic method for device size selection in patients undergoing ASD trans-catheter closure

The Egyptian Heart Journal, 2019
Background Proper device size selection is a crucial step for successful ASD device closure. The current gold standard for device size selection is balloon sizing. Balloon sizing can be tedious, time consuming and increase fluoroscopy and procedure times
Alaa Roushdy, Aya El sayegh, Yasmin Abdelrazek Ali, Hebattalla Attia, Azza El fiky, Maiy El sayed   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Cardiac parasympathetic denervation reduces hypoxic tachycardia, baroreflex sensitivity and heart rate variability in humans

Scientific Reports
The autonomic regulation of heart rate (HR) reactivity to acute hypoxia remains unclear. Parasympathetic cardioneuroablation (PCNA) may serve as a novel model for the analysis of physiological consequences of reduced vagal influence over sinus node in ...
Piotr Niewinski, Stanislaw Tubek, Krystian Josiak, Krzysztof Nowak, Piotr Ponikowski   +4 more
doaj   +1 more source

Females and Exercise Capacity Impairment in Heart Failure: A Sex-Focused Analysis

Journal of Cardiovascular Development and Disease
Heart failure (HF) is becoming increasingly common, especially in older females, and displays marked sex-related differences in pathophysiology, treatment, and outcomes. Submaximal exercise capacity (SEC), frequently measured by the six-minute walk test (
Ainhoa Lorenzo, Raúl Ramos-Polo, Laia Lorenzo-Esteller, Xinying Lin, Emma Barragan, Paula Aranda, Èlia Boixader, Foix Regull, Nerea Martín, Ariana Ollé, Marc Llagostera, Núria José-Bazán, Pedro Moliner, Cristina Enjuanes, Josep Comin-Colet   +14 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Lateral costal artery as a culprit for the steal phenomenon after coronary artery bypass grafting: a case report and review of the literature

Journal of Cardiothoracic Surgery
Background The left internal thoracic artery (LITA) has been widely accepted as the standard for revascularizing the left anterior descending artery during coronary artery bypass grafting (CABG) surgery.
Michal Trebišovský, Marián Homola, Adrián Kolesár, Štefan Lukačin, Anton Bereš   +4 more
doaj   +1 more source

Strengths and limitations of HFpEF probability scores in the era of precision medicine

Frontiers in Medicine
BackgroundHeart failure with preserved ejection fraction is a heterogeneous syndrome influenced by comorbidities, complicating diagnosis and treatment.
Michał Wilk, Tomasz Kotwica, Robert Zymliński, Piotr Gajewski   +3 more
doaj   +1 more source

Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study [PDF]

, 2014
BACKGROUND:\ud An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic.
Elizabeth A Barley, Mann, Anthony, Rachel Phillips, Tylee, Andre, Phillips, Rachel, Barley, Elizabeth A., Phillips, Rachel; id_orcid, Barley, Elizabeth, Paul Walters, André Tylee, Walters, Paul, Anthony Mann, Barley, Elizabeth A   +12 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source