Results 81 to 90 of about 1,425,667 (309)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Surveillance and evaluation data resource guide for heart disease and stroke prevention programs [PDF]
High blood pressure, high sodium intake, high cholesterol, and smoking continue to put more people at risk of heart disease and stroke. To address these risk factors, the CDC focuses on the ABCS of heart disease and stroke prevention\u2014appropriate ...
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Assessment of coronary heart diseases in diabetics in al-Madinah al-Munawarah [PDF]
, 2012 Omar al-Nozha1, Moaz Mojadadi2, Mohamed Mosaad1,3, Mohamed F El-Bab2,41Department of Medicine, 2Department of Physiology, College of Medicine, Taibah University, al-Madinah al-Munawarah, Kingdom of Saudi Arabia; 3Department of Medicine, 4Department of ...
al-Nozha O +3 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2015 Objective: To determine in hospital clinical outcome of primary PCI in elderly patients. Study Design: Descriptive cross-sectional study. Place and Duration of Study: This study was performed in Armed Force Institute of Cardiology from November ...
Imran Ghani +7 more
doaj +2 more sources
Journal of the American College of Cardiology, 2010 ![Figure][1] [![Graphic][3] ][3][![Graphic][4] ][4][![Graphic][5] ][5] A 26-year-old man with a history of carcinoid and small-bowel resection presented with shortness of breath.
Hong, Susie N. +2 more
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Milk, coronary heart disease and mortality [PDF]
, 2001 <b>STUDY OBJECTIVE</b> To study the association between reported milk consumption and cardiovascular and all cause mortality. <b>DESIGN</b> A prospective study of 5765 men aged 35-64 at the time of examination.
Davey Smith, G., Hart, C.L., Ness, A.
core +1 more source