Results 81 to 90 of about 1,419,649 (316)

Population assessment of future trajectories in coronary heart disease mortality.

, 2014
Background: Coronary heart disease (CHD) mortality rates have been decreasing in Iceland since the 1980s, largely reflecting improvements in cardiovascular risk factors. The purpose of this study was to predict future CHD mortality in Iceland based on
Aspelund, T, Thor Aspelund, Thorolfsdottir, Rosa Björk, Capewell, S, Rosa Björk Thorolfsdottir, Julia Critchley, Gudnason, Vilmundur, Aspelund Thor, Thor Aspelund (103668), Vilmundur Gudnason, Simon Capewell (21152), Karl Andersen (237469), Julia Critchley (237473), Gudnason, V, Critchley Julia, Vilmundur Gudnason (8873), Aspelund, Thor, Andersen Karl, Andersen, K, Gudnason Vilmundur, Simon Capewell, Rosa Björk Thorolfsdottir (511753), Thorolfsdottir, RB, Critchley, Julia, Andersen, Karl, Capewell Simon, Critchley, J, Capewell, Simon, Thorolfsdottir Rosa Björk, Karl Andersen   +29 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Surveillance and evaluation data resource guide for heart disease and stroke prevention programs [PDF]

High blood pressure, high sodium intake, high cholesterol, and smoking continue to put more people at risk of heart disease and stroke. To address these risk factors, the CDC focuses on the ABCS of heart disease and stroke prevention\u2014appropriate ...

core  

Eigenhearts for diagnosis of congestive heart failure (CHF)

, 2006
Common cardiac diseases such as cardio-myopathy, coronary artery diseases, and valve diseases, result in abnormal myocardial movement, which could eventually lead to heart failure, also called congestive heart failure (CHF). CHF is a disease in which the
V. Ahanathapillai, Hamilton, David, Ahanathapillai, Vijayalakshmi, D.J. Hamilton   +3 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Impact of iron deficiency on left ventricular noninvasive myocardial work indices in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation

Cardiology Journal
BACKGROUND: Aortic stenosis (AS) increases left ventricular (LV) afterload and systolic pressure (LVSP). Left ventricular myocardial work (LVMW) enables early detection of LV dysfunction.
Michał J. Błaszkiewicz, Tomasz G. Witkowski, Wojciech Bombała, Michał Kosowski, Piotr Kübler, Krzysztof Reczuch, Krzysztof Aleksandrowicz, Ewa A. Jankowska, Marcin Protasiewicz   +8 more
doaj   +1 more source

Carcinoid Heart Disease

Journal of the American College of Cardiology, 2010
![Figure][1] [![Graphic][3] ][3][![Graphic][4] ][4][![Graphic][5] ][5] A 26-year-old man with a history of carcinoid and small-bowel resection presented with shortness of breath.
Hong, Susie N., Saric, Muhamed, Kronzon, Itzhak   +2 more
openaire   +2 more sources

Milk, coronary heart disease and mortality [PDF]

, 2001
<b>STUDY OBJECTIVE</b> To study the association between reported milk consumption and cardiovascular and all cause mortality. <b>DESIGN</b> A prospective study of 5765 men aged 35-64 at the time of examination.
Davey Smith, G., Hart, C.L., Ness, A.
core   +1 more source