Results 81 to 90 of about 4,754,184 (293)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

PROCEDURAL OUTCOME OF PRIMARY PCI INST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AT AFIC & NIHD RAWALPINDI – PAKISTAN

open access: yesPakistan Armed Forces Medical Journal, 2014
Objective: To determine the procedural outcome of primary percutaneous coronary interventions (PCI) in ST segment elevation myocardial infarction. Study Design: A quasi-experimental study.
Naseer Ahmad Samore   +7 more
doaj   +2 more sources

MANAGEMENT OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION COMPLICATED BY VENTRICULAR SEPTAL RUPTURE - AFIC STUDY

open access: yesPakistan Armed Forces Medical Journal, 2014
Objective: The aim of this study was to report management; peri-procedural and short term results of patients hospitalized with acute myocardial infarction (MI)complicated by ventricular septal rupture (VSR) considered high risk or unfit for surgical ...
Abdul Hameed Siddiqui   +7 more
doaj   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Rheumatic heart disease and acute rheumatic fever in Australia: 1996-2011 [PDF]

open access: yes, 2013
Acute rheumatic fever (ARF) is rare in most developed countries, but rates among Aboriginal and Torres Strait Islander people are among the highest in the world based on available data. Rheumatic heart disease (RHD), which can be prevented by adequate

core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Rationale, design and conduct of a randomised controlled trial evaluating a primary care-based complex intervention to improve the quality of life of heart failure patients: HICMan (Heidelberg Integrated Case Management) : study protocol [PDF]

open access: yes, 2007
Background: Chronic congestive heart failure (CHF) is a complex disease with rising prevalence, compromised quality of life (QoL), unplanned hospital admissions, high mortality and therefore high burden of illness. The delivery of care for these patients
Herzog, Wolfgang   +20 more
core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Diuretic treatment using the RenalGuard® system in patients hospitalized due to acute decompensated heart failure and characterization of the profile of patients with good and poor response to treatment — preliminary study

open access: yesCardiology Journal
BACKGROUND: The aim of the study was to analyze the potential relationship between the diuretic response, the clinical profile and the concentrations of selected biochemical markers and to identify a group of patients who will benefit from a new form of ...
Paweł Siwołowski   +6 more
doaj   +1 more source

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