Results 41 to 50 of about 1,419,649 (316)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Scleroderma Heart Disease

International Journal of Immunopathology and Pharmacology, 2005
Heart disease is a frequent and often severe feature of systemic sclerosis (scleroderma). Cardiomyopathy, with ventricular diastolic dysfunction and arrhythmias, is the most important form, since it is associated with a very poor prognosis. The current challenge is to define its pattern and identify individuals at risk, but evaluation in vivo may be ...
B. Marasini, M. Massarotti, R. Cossutta
openaire   +3 more sources

Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study. [PDF]

, 2011
AIMS: A higher intake of fruits and vegetables has been associated with a lower risk of ischaemic heart disease (IHD), but there is some uncertainty about the interpretation of this association.
M.-J. Tormo, Roddam, AW, L. Rodriguez, Pala, V., Beulens, J. W. J., A. Trichopoulou, Danesh, J, P. Lagiou, Key, Timothy, Romieu, I, N. J. Wareham, Panico, S, Sacerdote, C., Tjønneland, A, Buckland, G., Riboli, E., N. Larranaga, Lagiou, P, Beulens, Joline W. J., Jenab, M, Buckland, Genevieve, R. Tumino, Palli, Domenico, E. Lund, P. N. Appleby, Bueno-de-Mesquita, H. Bas, A. Barricarte, Overvad, K., H. B. Bueno-de-Mesquita, null null, Sacerdote, Carlotta, Linseisen, Jakob, C. Weikert, Melander, Olle,, Panico, Salvatore, Slimani, Nadia, Hedblad, Bo, Jenab, M., Key, T. J., Hansen, L, Larrañaga, Nerea, Barricarte, A, Weikert, Cornelia, Slimani, N, van Gils, van, I. Romieu, Linseisen, J, D. Palli, Misirli, G., Crowe, F. L., P. Wennberg, J. Linseisen, Trichopoulou, A., V. Pala, A. Tjonneland, Wennberg, P, J. Danesh, Tormo, María José, Misirli, G, Crowe, FL, M. Jenab, Rodriguez, L., Wareham, Nicholas J, Norat, T., Danesh, J., Lagiou, Pagona, Panico, S., Tumino, R., Barricarte, Aurelio, Lagiou, P., Trichopoulou, Antonia, Lund, Eiliv, Bueno-de-Mesquita, H. B., Roddam, A. W., Jakobsen, M. U., Riboli, E, Riboli, Elio, A. W. Roddam, Sánchez, Maria José, Tumino, Rosario, Gallo, V., J.-H. Jansson, H. Boeing, European Prospective Investigation into Cancer and Nutrition (EP, Gallo, V, Tormo, M.-J., Key, Timothy J, Norat, T, G. Buckland, Sánchez, Maria-José, Crowe, Francesca L., C. Sacerdote, Wennberg, P., Sanchez, M.-J., J. W. J. Beulens, Overvad, Kim, Overvad, K, Sacerdote, C, Jakobsen, Marianne U., Boer, J., Hedblad, B, Palli, D., Sánchez, MJ, Appleby, PN, Pala, Valeria, Hedblad, Bo,, Beulens, Joline W J, Crowe, Francesca L, Boeing, Heiner, Roddam, Andrew W, Bueno-de-Mesquita, HB, Tjonneland, Anne, T. Norat, G. Misirli, S. Panico, Jansson, Jan-Håkan,, Palli, D, Slimani, N., Larranaga, N., Beulens, JW, Bueno-de-Mesquita, H Bas, Key, Timothy J., Jansson, JH, Hansen, L., Key, TJ, Appleby, Paul N, Misirli, Gesthimani, Jenab, Mazda, R. Kaaks, Roddam, Andrew W., Melander, O., Lund University., Kaaks, Rudolf, Tjonneland, A., Jansson, Jan Hkan, Beulens, Joline W.J., B. Hedblad, E. Riboli, Boeing, H, Jansson, J.-H., Danesh, John, T. J. Key, Jansson, Jan-Håkan, Jakobsen, Marianne U, N. Slimani, Tormo, MJ, Tjønneland, Anne, O. Melander, Trichopoulou, A, van Gils, C. H., Wareham, N. J., Weikert, C, Wareham, NJ, Romieu, I., Tormo, María-José, Melander, O, van Gils, CH, Hedblad, B., M. U. Jakobsen, Gallo, Valentina, V. Gallo, van Gils, Carla H, Melander, Olle, Weikert, C., Romieu, Isabelle, Jakobsen, MU, Wareham, Nicholas J., Rodríguez, Laudina, L. Hansen, Hansen, Louise, van Gils, Carla H., Rodríguez, L, Boer, J, J. Boer, Boer, Jolanda, Appleby, Paul N., Lund, E., Larrañaga, N, F. L. Crowe, Wennberg, Patrik, Pala, V, Barricarte, A., Norat, Teresa, Appleby, P. N., K. Overvad, Lund, E, Boeing, H., Tumino, R, Buckland, G, C. H. van Gils, M.-J. Sanchez, Wennberg, Patrik,, Kaaks, R, Kaaks, R., Beulens, Joline WJ   +194 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Implications of prognostic nutritional index in predicting adverse outcomes of uncontrolled diabetic patients: a cohort study of the national health and nutrition examination survey from 2005 – 2018

Diabetology & Metabolic Syndrome
Background Diabetes mellitus (DM) is a metabolic disorder with increasing prevalence and poor control rates, leading to adverse events. Prognostic nutritional value (PNI) has been identified as a protective factor in DM, but its role in uncontrolled DM ...
Fei Liu, Zhili Jiang, Wei Luo, Yunxiao Yang, Shuai Guo, Jiayi Yi, Geng Shen, Wei Li, Lin Wang, Xiuhuan Chen, Zhaogong Zhi, Tian Liu, Xuedong Zhao, Chen Li, Hai Gao   +14 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Rheumatic heart disease and acute rheumatic fever in Australia: 1996-2011 [PDF]

, 2013
Acute rheumatic fever (ARF) is rare in most developed countries, but rates among Aboriginal and Torres Strait Islander people are among the highest in the world based on available data. Rheumatic heart disease (RHD), which can be prevented by adequate

core  

Analysing the Large Decline in Coronary Heart Disease Mortality in the Icelandic Population Aged 25-74 between the Years 1981 and 2006.

, 2010
BACKGROUND: Coronary heart disease (CHD) mortality rates have been decreasing in Iceland since the 1980s. We examined how much of the decrease between 1981 and 2006 could be attributed to medical and surgical treatments and how much to changes in ...
Aspelund, T, Thor Aspelund, Capewell, S, Sigurdsson, G, Magnusdottir, BT, Julia Critchley, Kathleen Bennett, Gudnason, Vilmundur, Aspelund Thor, Magnusdottir Bergrun Tinna, O'Flaherty, Martin, Vilmundur Gudnason, Thorsson, B, Bolli Thorsson, Gudnason, V, Critchley Julia, Thorsson, Bolli, Bennett, Kathleen, Aspelund, Thor, Magnusdottir, Bergrun Tinna, Andersen Karl, O'Flaherty, M, Bergrun Tinna Magnusdottir, Andersen, K, Thorsson Bolli, Gudnason Vilmundur, Simon Capewell, Steingrimsdottir, L, Sigurdsson Gunnar, Bennett Kathleen, Martin O'Flaherty, Critchley, Julia, Andersen, Karl, Capewell Simon, Critchley, J, Gunnar Sigurdsson, Capewell, Simon, Steingrimsdottir, Laufey, O'Flaherty Martin, Bennett, K, Sigurdsson, Gunnar, Steingrimsdottir Laufey, Laufey Steingrimsdottir, Karl Andersen   +43 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source