Results 51 to 60 of about 4,967,645 (304)

Scleroderma Heart Disease

International Journal of Immunopathology and Pharmacology, 2005
Heart disease is a frequent and often severe feature of systemic sclerosis (scleroderma). Cardiomyopathy, with ventricular diastolic dysfunction and arrhythmias, is the most important form, since it is associated with a very poor prognosis. The current challenge is to define its pattern and identify individuals at risk, but evaluation in vivo may be ...
B. Marasini, M. Massarotti, R. Cossutta
openaire   +3 more sources

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

On Fatty Diseases of the Heart [PDF]

Journal of the Royal Society of Medicine
n ...
openaire   +4 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Irish Heart Foundation position statement on salt, blood pressure and heart disease [PDF]

, 2004
stroke and related diseases of blood vessels.1, 2 CVD the single largest cause of death in Ireland 3. There is now convincing evidence that sodium intake, mainly through dietary salt (sodium chloride), is directly associated with blood pressure. 1,2, 4,
Irish Heart Foundation (IHF)
core  

Heart diseases, pulmonary and liver condition details.

, 2023
Heart diseases, pulmonary and liver condition details.
Jean-Sébastien Vidal (249552), Laurent Becquemont (2579197), Edouard Baudouin (11898983), Emmanuelle Corruble (2865488), Emmanuelle Duron (11898986), Sarah Zitoun (11898980)   +5 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

RNAs in Brain and Heart Diseases

, 2020
In the era of single-cell analysis, one always has to keep in mind the systemic nature of various diseases and how these diseases could be optimally studied.
Dimitris Beis, Inga Zerr, Yvan Devaux, Wolfram Doehner, Fabio Martelli   +4 more
core   +1 more source

Post-LVAD diuretic trajectories and predictors of diuretic resistance

Journal of Cardiothoracic Surgery
Background Renal dysfunction and diuretic resistance may persist or develop after left ventricular assist device (LVAD) implantation despite restoration of cardiac output (CO). This study aimed to characterize post-LVAD diuretic trajectories and identify
Saša Borović, Dragana Kosević, Jelena Stefanović Nesković, Mehmet Hakan Akay, Jovan Petrović, Petar Dabić, Nadiia Rineiska, Milovan Bojić   +7 more
doaj   +1 more source