Results 101 to 110 of about 2,773,922 (357)
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na+4 more
wiley +1 more source
Activity Theory Analysis of Heart Failure Self-Care [PDF]
The management of chronic health conditions such as heart failure is a complex process emerging from the activity of a network of individuals and artifacts.
Cornet, Victor+2 more
core +1 more source
Background Approximately 2–3% of patients undergoing advanced heart failure therapies such as left ventricular assist devices (LVAD) and orthotropic heart transplantation (OHT) have chemotherapy-related cardiomyopathy, according to analyses of large ...
Raquel Araujo-Gutierrez+8 more
doaj +1 more source
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen+14 more
wiley +1 more source
Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis [PDF]
Objective: First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR interval may be associated with adverse outcomes. This study
Barker, Diane+11 more
core +1 more source
‘Mitotherapy’ for Heart Failure
Abnormalities in mitochondrial dynamics along with those for the molecular mediators involved are presently being viewed with increased interest in the field of cardiovascular disease. Recent research highlights OPA1, a dynamin-like GTPase mediating mitochondrial fusion, as well as the 'mitoproteases' OMA1 and YME1L, as potential therapeutic targets ...
Sanchis Gomar, Fabian+2 more
openaire +6 more sources
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard+15 more
wiley +1 more source
Heart Rate Variability: A possible machine learning biomarker for mechanical circulatory device complications and heart recovery [PDF]
Cardiovascular disease continues to be the number one cause of death in the United States, with heart failure patients expected to increase to \u3e8 million by 2030.
Aras, Shravan+2 more
core +1 more source
Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis [PDF]
The effect of a sodium glucose cotransporter 2 inhibitor (SGLT2i) in reducing heart failure hospitalization in the EMPA-REG OUTCOMES trial has raised the possibility of using these agents to treat established heart failure.
De Vecchis+22 more
core +1 more source
[Objective] To investigate the correlation of mitochondrial DNA copy number (mtDNAcn), Klotho protein, myostatin (MSTN) and their combination with physical frailty in elderly patients with sarcopenia.
Zhou Yanyan+5 more
doaj +1 more source