Results 101 to 110 of about 1,246,092 (314)
Heart Failure in Indonesia: A Growing Burden Beyond Conventional Care
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Vebiona Kartini Prima Putri +2 more
doaj +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Heart failure (HF) is rapidly growing, conferring considerable mortality, morbidity, and costs. Dedicated HF clinics improve patient outcomes, and the development of a national HF clinics network aims at addressing this need at national level.
The Task force of the Hellenic Heart Failure Clinics Network
doaj +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
High‐Sensitivity Troponin: A Clinical Blood Biomarker for Staging Cardiomyopathy in Fabry Disease
BackgroundHigh‐sensitivity troponin (hs‐TNT), a biomarker of myocardial damage, might be useful for assessing fibrosis in Fabry cardiomyopathy. We performed a prospective analysis of hs‐TNT as a biomarker for myocardial changes in Fabry patients and a ...
Nora Seydelmann +11 more
doaj +1 more source
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Pharmacotherapy of heart failure [PDF]
This thesis wrote about the pharmacological drugs of the heart failure. Their mechanism of effects and side effects and clinical effects. Pathophysiology aspects of the heart failure is written in the thesis. Epidemiology of heart failure is also deal in
Hwang, Seong Chan Jr
core
Eigenhearts for diagnosis of congestive heart failure (CHF) [PDF]
Common cardiac diseases such as cardio-myopathy, coronary artery diseases, and valve diseases, result in abnormal myocardial movement, which could eventually lead to heart failure, also called congestive heart failure (CHF). CHF is a disease in which the
V. Ahanathapillai +3 more
core +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Phosphodiesterase-5 inhibition in heart failure with preserved ejection fraction : trading therapy for prevention [PDF]
This article refers to 'Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase-5A inhibitor vardenafil in rats with type 2 diabetes,' by C.Matyas et al., published in this issue on pages 326 ...
Paulus, Walter J. +8 more
core +1 more source

