Results 171 to 180 of about 67,047,750 (228)

Advanced imaging and multi‐omics to characterize cardiomyocyte ageing and its electrocardiographic imprint in PKP2 arrhythmogenic cardiomyopathy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used a murine model of cardiomyocyte‐specific conditional knockout of plakophilin 2 (PKP2cKO, middle panel). Using advanced imaging technology, we unveiled distinct hallmarks of premature ageing in PKP2cKO cardiomyocytes, including DNA damage and loss of repressed heterochromatin at the nuclear periphery, and mitochondrial ...
Giorgia Bertoli   +12 more
wiley   +1 more source

Multiscale four‐dimensional imaging of cardiac remodelling after myocardial infarction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Multiscale 4D imaging framework for integrated phenotyping of post‐infarction remodelling. Myocardial infarction triggers dynamic changes across mechanical, haemodynamic and biological axes, progressing from acute injury and inflammation to extracellular matrix remodelling and scar maturation.
Hanzhou Lei, Boris Martinac, Yang Guo
wiley   +1 more source

Myocardial stretch‐induced ROS production is enhanced prior to the development of heart failure under TAC‐induced pressure overload

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend To elucidate the relationship between oxidative stress in heart failure induced by chronic mechanical overload and physiological NOX2‐derived stretch‐induced reactive oxygen species (ROS) that support myocardial contractility during acute stretch, we investigated the changes in stretch‐induced ROS following transverse aortic ...
Yumiko Chiba   +4 more
wiley   +1 more source

“Two‐For‐One”: 4D Cardiac and Pulmonary MR Imaging From a Single Acquisition Using bSTAR

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 5, Page 2213-2227, November 2026.
ABSTRACT Purpose To generate 4D (3D+time) images of both the heart and lungs using a single volumetric radial free‐breathing bSSFP dual echo acquisition (bSTAR) with two image reconstructions within a single pipeline deployed inline at 0.55 and 1.5 T.
Pierre Daudé   +9 more
wiley   +1 more source

Fulminant brachycephalic obstructive airway syndrome in a 3‐month‐old French bulldog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐month‐old, entire, female French bulldog (6.4 kg) presented in severe respiratory distress with hyperthermia and cyanosis. Laryngeal examination revealed severe obstruction by oedematous tissue, later confirmed as bilaterally everted laryngeal saccules; the airway was stabilised by tracheal intubation.
Yasumasa Iimori   +4 more
wiley   +1 more source

Home at the Margins: Police Violence, Evictions, and the Resistance to Belonging in São Paulo's ‘Cracolândia’

open access: yesPoLAR: Political and Legal Anthropology Review, Volume 49, Issue 2, November 2026.
ABSTRACT In São Paulo's Cracolândia—one of the world's largest open‐air drug scenes—urban transformation operates not through direct expulsion but through the systematic erosion of territorial bonds. Drawing on twenty months of ethnographic research with unhoused crack users, NGO workers, and state officials, this article examines how interactions with
Flávio Eiró, Giordano Magri
wiley   +1 more source

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