Results 1 to 10 of about 123,214 (256)

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction [PDF]

New England Journal of Medicine, 2019
In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms. More data are needed regarding the effects of SGLT2 inhibitors in patients with established heart failure and a reduced ejection fraction, regardless of the
, Sergey Tereshchenko, Claes Held
exaly   +14 more sources

Heart failure with reduced ejection fraction

Nature Reviews Disease Primers, 2017
Heart failure is a global public health problem that affects more than 26 million people worldwide. The global burden of heart failure is growing and is expected to increase substantially with the ageing of the population. Heart failure with reduced ejection fraction accounts for approximately 50% of all cases of heart failure in the United States and ...
Javed Butler, , Barry Greenberg
exaly   +7 more sources

Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction

New England Journal of Medicine, 2020
BACKGROUND The effect of vericiguat, a novel oral soluble guanylate cyclase stimulator, in patients with heart failure and reduced ejection fraction who had recently been hospitalized or had received intravenous diuretic therapy is unclear. METHODS In this phase 3, randomized, double-blind, placebo-controlled trial, we assigned 5050 patients with ...
Kevin Anstrom, Javed Butler, Paul Armstrong   +2 more
exaly   +9 more sources

Determinants of ejection fraction improvement in heart failure patients with reduced ejection fraction

ESC Heart Failure, 2023
Aims This study aimed to investigate the prognostic value of dynamic changes in left ventricular ejection fraction (EF) for cardiovascular (CV) outcomes in an all‐comer heart failure (HF) population with reduced EF (HFrEF, EF 4 vs.
Dan Liu, Kai Hu, Lena Schregelmann, Clara Hammel, Björn Daniel Lengenfelder, Georg Ertl, Stefan Frantz, Peter Nordbeck   +7 more
doaj   +3 more sources

Prognostic Value of Anxiety Between Heart Failure With Reduced Ejection Fraction and Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Evidence suggests differences in clinical characteristics, causes, and prognoses between heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).
Tin‐Kwang Lin, Bo‐Cheng Hsu, Yi‐Da Li, Chi‐Hsien Chen, Jiunn‐Wen Lin, Chen‐Yu Chien, Chia‐Ying Weng   +6 more
doaj   +3 more sources

Prevalence and Long‐Term Survival After Coronary Artery Bypass Grafting in Women and Men With Heart Failure and Preserved Versus Reduced Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Heart failure (HF) with reduced ejection fraction (rEF) is a widely regarded prognosticator after coronary artery bypass grafting. HF with preserved ejection fraction (pEF) accounts for up to half of all HF cases and is associated with ...
Louise Y. Sun, Jack V. Tu, Anan Bader Eddeen, Peter P. Liu   +3 more
doaj   +3 more sources

Interpretation of the Essential Updates in 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure [PDF]

Zhongguo quanke yixue, 2022
The American Heart Association (AHA) , American College of Cardiology (ACC) and Heart Failure Society of America (HFSA) jointly released the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure (hereinafter referred to as the 2022 Guideline) .
Yifang GUO
doaj   +1 more source

Vericiguat for Heart Failure with Reduced Ejection Fraction [PDF]

Current Cardiology Reports, 2021
AbstractPurpose of ReviewThe nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) pathway plays an important role in the regulation of cardiovascular function, and it is disrupted in heart failure (HF), resulting in decreased protection against myocardial injury.
Lombardi C. M., Cimino G., Pagnesi M., Dell'Aquila A., Tomasoni D., Ravera A., Inciardi R., Carubelli V., Vizzardi E., Nodari S., Emdin M., Aimo A.   +11 more
openaire   +4 more sources

Association of Depression and Anxiety with Cardiac Structural and Functional Characteristics in Heart Failure with Reduced and Mildly Reduced Ejection Fraction

Clinics and Practice, 2023
Heart failure and mental health conditions frequently coexist and have a negative impact on health-related quality of life and prognosis. We aimed to evaluate depression and anxiety symptoms and to determine the association between psychological distress
Timea Magdolna Szabo, Előd Ernő Nagy, Ádám Kirchmaier, Erhard Heidenhoffer, Hunor-László Gábor-Kelemen, Marius Frăsineanu, Attila Frigy   +6 more
doaj   +1 more source

Metabolomics and a Breath Sensor Identify Acetone as a Biomarker for Heart Failure

Biomolecules, 2022
Background: Multi-omics delivers more biological insight than targeted investigations. We applied multi-omics to patients with heart failure with reduced ejection fraction (HFrEF).
Patrick A. Gladding, Maxine Cooper, Renee Young, Suzanne Loader, Kevin Smith, Erica Zarate, Saras Green, Silas G. Villas Boas, Phillip Shepherd, Purvi Kakadiya, Eric Thorstensen, Christine Keven, Margaret Coe, Mia Jüllig, Edmond Zhang, Todd T. Schlegel   +15 more
doaj   +1 more source