Results 11 to 20 of about 187,398 (301)
Spironolactone for Heart Failure with Preserved Ejection Fraction [PDF]
New England Journal of Medicine, 2014 BACKGROUND: Mineralocorticoid-receptor antagonists improve the prognosis for patients with heart failure and a reduced left ventricular ejection fraction.
Bertram Pitt +2 more
exaly +3 more sources
Heart failure with reduced ejection fraction
Nature Reviews Disease Primers, 2017 Heart failure is a global public health problem that affects more than 26 million people worldwide. The global burden of heart failure is growing and is expected to increase substantially with the ageing of the population. Heart failure with reduced ejection fraction accounts for approximately 50% of all cases of heart failure in the United States and ...
Bloom, Michelle W. +7 more
exaly +8 more sources
Neurohormonal activation in heart failure with reduced ejection fraction [PDF]
Nature Reviews Cardiology, 2016 Heart failure with reduced ejection fraction (HFrEF) develops when cardiac output falls as a result of cardiac injury. The most well-recognized of the compensatory homeostatic responses to a fall in cardiac output are activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS).
Justin, Hartupee, Douglas L, Mann
openaire +4 more sources
Biomarker profiles of acute heart failure patients with a mid-range ejection fraction [PDF]
, 2017 OBJECTIVES: In this study, the authors used biomarker profiles to characterize differences between patients with acute heart failure with a midrange ejection fraction (HFmrEF) and compare them with patients with a reduced (heart failure with a ...
Bloomfield, Daniel M +16 more
core +15 more sources
ESC Heart Failure, 2022 Aims Available evidence is incomplete and inconsistent in the outcomes of heart failure (HF) patients with preserved ejection fraction (HFpEF), mildly reduced ejection fraction (HFmrEF), and reduced ejection fraction (HFrEF).
Shiqun Chen +15 more
doaj +1 more source
Indian Pacing and Electrophysiology Journal, 2022 Background: This review aims to determine if patients who undergo atrial fibrillation (AF) ablation with heart failure with preserved ejection fraction (HFpEF) do better, or worse or the same compared to patients with heart failure with reduced ejection ...
Gaurav Panchal +4 more
doaj +1 more source
Cells, 2022 Recent studies have shown that circulating levels of irisin are prognostic factors in heart failure (HF), but no data are available on the predictive role of irisin in patients with type 2 diabetes mellitus (T2DM) and different phenotypes of HF.
Alexander A. Berezin +4 more
doaj +1 more source
Sirt1 Activity in PBMCs as a Biomarker of Different Heart Failure Phenotypes
Biomolecules, 2020 Heart Failure (HF) is a syndrome, which implies the existence of different phenotypes. The new categorization includes patients with preserved ejection fraction (HFpEF), mid-range EF (HFmrEF), and reduced EF (HFrEF) but the molecular mechanisms involved ...
Valeria Conti +14 more
doaj +1 more source
ESC Heart Failure, 2020 Currently, the assessment of left ventricular ejection fraction (LVEF) is the cornerstone of the classification of patients with heart failure (HF). The mid‐range LVEF (HFmrEF) category was identified in an attempt to uncover specific characteristics of ...
Luca Branca +3 more
doaj +1 more source
Therapeutic Stalemate in Heart Failure With Preserved Ejection Fraction
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 The findings of randomized trials of neurohormonal modulation have been neutral in heart failure with preserved ejection fraction and consistently positive in heart failure with reduced ejection.
Rohan Samson, Thierry H. Le Jemtel
doaj +1 more source