Urinary proteomics pilot study for biomarker discovery and diagnosis in heart failure with reduced ejection fraction [PDF]
Background Biomarker discovery and new insights into the pathophysiology of heart failure with reduced ejection fraction (HFrEF) may emerge from recent advances in high-throughput urinary proteomics.
Bosselmann, Helle Skovmand +10 more
core +8 more sources
SGLT2 inhibitors in heart failure with reduced ejection fraction [PDF]
AbstractSodium – glucose co-transporter 2 (SGLT2) inhibitors reduce blood glucose by inhibiting reabsorption of glucose from the proximal renal tubules. Initial studies showed that apart from reducing blood glucose they also reduce the combined endpoint of myocardial infarction, stroke, and cardiovascular death, hospitalization from heart failure, and ...
U. Das, A Paul, Suvro Banerjee
openaire +3 more sources
Cardiac sympathetic dysfunction in pulmonary arterial hypertension: Lesson from left-sided heart failure [PDF]
Sympathetic nervous system hyperactivity has a well-recognized role in the pathophysiology of heart failure with reduced left ventricular ejection fraction.
Bonaduce, Domenico +10 more
core +1 more source
BackgroundDespite advances in diagnosing and treating chronic heart failure (HF), the underlying mechanisms in different HF phenotypes remain unclear. Mitochondrial energy metabolism is crucial in HF etiology.
Shiwen Zhang +6 more
doaj +1 more source
Secondary valve regurgitation in patients with heart failure with preserved ejection fraction, heart failure with mid-range ejection fraction, and heart failure with reduced ejection fraction [PDF]
Abstract Secondary mitral regurgitation and secondary tricuspid regurgitation due to heart failure (HF) remain challenging in almost every aspect: increasing prevalence, poor prognosis, notoriously elusive in diagnosis, and complexity of therapeutic management.
Philipp E Bartko +8 more
openaire +3 more sources
Heart failure with preserved ejection fraction. [PDF]
Heart failure with preserved ejection fraction (HFpEF) has recently emerged as a major cause of cardiovascular morbidity and mortality. Contrary to initial beliefs, HFpEF is now known to be as common as heart failure with reduced ejection fraction (HFrEF)
ElGuindy, A, Yacoub, MH
core +1 more source
Aims Evidence on the association between ambient temperature and the onset of acute heart failure (AHF) is scarce and mixed. We sought to investigate the incidence of AHF admissions based on ambient temperature change, with particular interest in ...
Takahiro Jimba +19 more
doaj +1 more source
Microvascular Disease with Heart Failure with Reduced and Preserved Ejection Fraction in Patients with Type 2 Diabetes [PDF]
Aims: Identification of patients with type 2 diabetes (T2D) at increased risk of incident heart failure (HF) beyond traditional risk factors such as prior myocardial infarction (MI) might allow selection of patients who would benefit from preventative ...
Doney, Alexander +5 more
core +2 more sources
Background Because of advances in medical treatments, a substantial proportion of patients with heart failure (HF) have experienced recovery of ejection fraction (EF), termed HF with recovered EF (HFrecEF).
Chen Die Yang +11 more
doaj +1 more source
Cardiac metabolism — A promising therapeutic target for heart failure [PDF]
Both heart failure with reduced ejection fraction (HFrEF) and with preserved ejection fraction (HFpEF) are associated with high morbidity and mortality.
Frenneaux, Michael P +3 more
core +2 more sources

