Results 131 to 140 of about 37,314 (262)

Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction [PDF]

, 2018
Background: Information on the pathophysiological differences between heart failure with reduced ejection fraction (HFrEF) versus heart failure with preserved ejection fraction (HFpEF) is needed Objectives: The purpose of this study was to establish ...
Anker, Stefan D., Cleland, John G. F., Dickstein, Kenneth, Filippatos, Gerasimos S., Hillege, Hans L., Lang, Chim, Metra, Marco, Ng, Leong Loke, Ouwerkerk, Wouter, Ponikowski, Piotr, Samani, Nilesh J., Tromp, Jasper, van der Harst, Pim, van der Meer, Peter, van Veldhuisen, Dirk Jan, Voors, Adriaan A., Westenbrink, Daan, Zannad, Faiez, Zwinderman, Aelko H.   +18 more
core   +3 more sources

Cardiogenic shock mortality according to Aetiology in a Mediterranean cohort: Results from the Shock‐CAT study

ESC Heart Failure, Volume 12, Issue 2, Page 1336-1345, April 2025.
Abstract Aims Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was to investigate in‐hospital prognosis and mortality in CS patients according to aetiology. We also assessed the prognostic accuracy of CardShock and IABP‐SHOCK II scores.
Cosme García‐García, Teresa López‐Sobrino, Esther Sanz‐Girgas, Maria R. Cueto, Jaime Aboal, Pablo Pastor, Irene Buera, Alessandro Sionis, Rut Andrea, Judit Rodríguez‐López, Jose Carlos Sánchez‐Salado, Carlos Tomas, Jordi Bañeras, Albert Ariza, Josep Lupón, Antoni Bayés‐Genís, Ferran Rueda, Grup de Treball de Cures Agudes Cardiològiques Societat Catalana de Cardiologia   +17 more
wiley   +1 more source

Effect of sacubitril valsartan on heart failure with mid-range or preserved ejection fraction in patients on maintenance hemodialysis: real-world experience in a single-center, prospective study

BMC Cardiovascular Disorders
Background This study aimed to evaluate the effect of sacubitril valsartan (SV) on heart failure (HF) hospitalization and cardiovascular mortality in patients on hemodialysis with HF with preserved ejection fraction (EF; HFpEF).
Xiao-mei Huang, Jing-jing Li, Wang Yin, Hui-ling Fu, Fen Yu, Lian-qing Gu, Yi Zhang, Min Du, Zheng Ye, Li Xu   +9 more
doaj   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

β-blocker and 1-year outcomes among patients hospitalized for heart failure with mid-range ejection fraction. [PDF]

Eur Heart J Cardiovasc Pharmacother, 2022
Wang B, Zhang L, Hu S, Bai X, Zhang H, Li X, Li J, Zheng X.   +7 more
europepmc   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Prognostic Value of Epicardial Adipose Tissue in Heart Failure With Mid‐Range and Preserved Ejection Fraction: A Multicenter Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Epicardial adipose tissue (EAT) accumulation is thought to play a role in the pathophysiology of heart failure (HF) with mid‐range ejection fraction and HF with preserved ejection fraction, but its effect on outcome is unknown.
Wenxian Wang, Yan Gao, Jian Wang, Congshan Ji, Hui Gu, Xianshun Yuan, Shifeng Yang, Ximing Wang   +7 more
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Treatment of Heart Failure with Mid-Range Ejection Fraction: What Is the Evidence. [PDF]

J Clin Med, 2021
Koufou EE, Arfaras-Melainis A, Rawal S, Kalogeropoulos AP.   +3 more
europepmc   +1 more source

Heart Failure With Mid-Range (Borderline) Ejection Fraction: Clinical Implications and Future Directions.

JACC. Heart failure, 2017
Heart failure (HF) with borderline ejection fraction was first defined in 2013 in the American College of Cardiology/American Heart Association guidelines as the presence of the typical symptoms of HF and a left ventricular ejection fraction (LVEF) of 41% to 49%. In 2016, the European Society of Cardiology specified HF with mid-range ejection fraction (
Hsu, Jeffrey J, Ziaeian, Boback, Fonarow, Gregg C   +2 more
openaire   +5 more sources