Results 191 to 200 of about 2,227,737 (406)

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang   +8 more
wiley   +1 more source

Differences in blood pressure riser pattern in patients with acute heart failure with reduced mid‐range and preserved ejection fraction

open access: yesESC Heart Failure, 2019
Aims Heart failure (HF) is classified into three types according to left ventricular ejection fraction (EF). The effect of blood pressure (BP) on the pathogenesis of each type is assumed to be different.
Tomoya Ueda   +12 more
doaj   +1 more source

Chronic Kidney Disease and Outcomes in Heart Failure With Preserved Versus Reduced Ejection Fraction [PDF]

open access: bronze, 2013
David H. Smith   +9 more
openalex   +1 more source

SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials

open access: yesThe Lancet, 2020
F. Zannad   +10 more
semanticscholar   +1 more source

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim   +12 more
wiley   +1 more source

Pharmacological and Non-Pharmacological Advancements in Heart Failure Treatment

open access: yesReviews in Cardiovascular Medicine
Heart failure (HF) is a complex, life-threatening condition characterized by high mortality, morbidity, and poor quality of life. Despite studies of epidemiology, pathogenesis, and therapies, the rate of HF hospitalization is still increasing due to the ...
Chen Wang   +3 more
doaj   +1 more source

Development of Automated Neural Network Prediction for Echocardiographic Left ventricular Ejection Fraction [PDF]

open access: yesarXiv
The echocardiographic measurement of left ventricular ejection fraction (LVEF) is fundamental to the diagnosis and classification of patients with heart failure (HF). In order to quantify LVEF automatically and accurately, this paper proposes a new pipeline method based on deep neural networks and ensemble learning.
arxiv  

Effects of Exercise on Left Ventricular Systolic and Diastolic Properties in Patients With Heart Failure and a Preserved Ejection Fraction Versus Heart Failure and a Reduced Ejection Fraction [PDF]

open access: bronze, 2013
Michael R. Zile   +8 more
openalex   +1 more source

Functional Assessment of Heart Failure Patients

open access: yes, 2015
Heart failure (HF) is the condition characterized by the inability of the heart to pump sufficient blood to meet the demands of the body. It has been well established that both the prevalence and incidence of HF is increasing.1 There are 2 primary types ...
Imboden, Mary T., Kaminsky, Leonard A.
core   +1 more source

The FGF13‐Caveolin‐1 Axis: A Key Player in the Pathogenesis of Doxorubicin‐ and D‐Galactose‐Induced Premature Cardiac Aging

open access: yesAdvanced Science, EarlyView.
The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen   +15 more
wiley   +1 more source

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