Results 231 to 240 of about 1,900,908 (289)

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Association of Aspirin Use with In-Hospital Mortality in Patients with Radiation-Associated Acute Pneumonitis: Insights from the National Inpatient Sample Database. [PDF]

Healthcare (Basel)
Sharma A, Shalini, Balasubramanian S, Yousaf H, Agrawal A, Vyas V.   +5 more
europepmc   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

High-Velocity Drag Racing Collision Leading to Rare Superior Mesenteric Branch Injury: A Case Report. [PDF]

Spartan Med Res J
Evans C, Miller S, Jean Z, Ross M, Erhardt K, Buggia M.   +5 more
europepmc   +1 more source

[Heart injuries].

Gaceta medica de Mexico, 1999
openaire   +1 more source

High‐Throughput Mechanical Rupture of Nuclear Envelope and the Intracellular Dynamics of Massive Wound Repair

Advanced Science, EarlyView.
A microfluidic device with monolithically integrated nanostructures enables high‐throughput wounding of the cell membrane and nuclear envelope. The spatial distribution of charged multivesicular body protein 4B (CHMP4B) within the cell is mapped before and after wounding, showing involvement in repair of both the cell membrane and nuclear envelope ...
Apresio K. Fajrial, Leyla Akh, Stephanie E. Schneider, Wei Tan, Corey P. Neu, Xiaoyun Ding   +5 more
wiley   +1 more source

Emergency endovascular repair of blunt thoracic aortic injury-related pseudoaneurysm using a castor single-branched stent graft: a case report and literature review. [PDF]

Front Cardiovasc Med
Wang Y, Liu H, Zhang T, Mao M, Zhang H, Chen B, Tian X, Li Y.   +7 more
europepmc   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Right Ventricular Wound And Complete Mammary Artery Transection

Arquivos Brasileiros de Cardiologia
Gregorio Laguna, Miriam Blanco, Cristina García-Rico, Yolanda Carrascal   +3 more
doaj   +1 more source

Increased Risk of Injury in Patients with Fabry Disease: A Nationwide Population-Based Cohort Study in Taiwan. [PDF]

Int J Med Sci
Cheng CG, Chen YH, Chien WC, Chiu HW, Hung FH, Peng HP, Chung CH, Cheng CA.   +7 more
europepmc   +1 more source