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Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source
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Injuries to the heart

Injury, 1993
During a 12-year period, 36 patients with cardiac injuries were recorded. Nine suffered penetrating injuries, nine blunt ruptures and 18 contusions. Only two patients with blunt rupture survived, in contrast to six out of seven patients with stab wounds to the heart.
J, Aksnes   +3 more
exaly   +3 more sources

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