Results 51 to 60 of about 1,728,360 (297)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Hodgkin lymphoma as a rare cause of complete atrioventricular block: a case report

КардиоСоматика
INTRODUCTION: Complete atrioventricular block is a life-threatening condition that requires urgent intervention and pacemaker implantation. Determining the underlying cause of the block is essential for effective management. This article describes a rare
Ekaterina A. Pravkina, Dmitry S. Sinitsyn, Polina S. Vikulova, Ilya B. Glukhovets, Sergei V. Subbotin   +4 more
doaj   +1 more source

Why publish in SA Heart Journal

, 2017
SA Heart is listed by the Department of Education (DoE) as an Approved Journal since January 2009. This development is important, not only for the stature of the Journal, but also for practical reasons such as the subsidy from the DoE involved for ...
Heart Journal, SA, SA Heart Journal, SA Heart, Journal, SA Heart, Hitzeroth, Jens   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Left-Sided Angiosarcoma of Heart: A Rare Case [PDF]

Journal of Tehran University Heart Center, 2009
A 22-year-old man presented with exertional dyspnea commencing one month prior to his admission. Echocardiography revealed a non-homogenous mass, and the pathology examination of the pericardial biopsy was compatible with angiosarcoma.
Yahya Dadjoo, Davood Kazemi Saleh, Maryam Moshkani Farahani, Bahram Pishgoo   +3 more
doaj   +2 more sources

Case Report: A case of right ventricular metastasis from cervical cancer presenting with thrombocytopenia: the role of echocardiography and myocardial contrast echocardiography

Frontiers in Oncology
BackgroundCardiac metastasis from cervical cancer is rare and often presents with nonspecific symptoms, leading to diagnostic delays. This case highlights the role of myocardial contrast echocardiography (MCE) in detecting such metastases in long-term ...
Qian Yang, Dong Bai, Liming Bao, Lei Liang, Haijun Hou   +4 more
doaj   +1 more source

Trend of non-communicable disease mortality for three common conditions in the elderly population from 2002 to 2010: A population-based study in China

Chronic Diseases and Translational Medicine, 2015
Objective: There is a lack of data focusing on non-communicable disease (NCD) mortality in the Chinese elderly population over the past decade. Methods: Using mortality data from the Chinese Health Statistics, we explored the crude and age-standardized ...
Qian Li, Jin Guo, Xiao-Qing Cao, Xin Yuan, Ke-Qin Rao, Zhe Zheng, Zhi-Dong Liu, Sheng-Shou Hu   +7 more
doaj   +1 more source

Position paper on physical activity for children and young people

, 2001
The National Heart Alliance is an independent non-governmental organisation which aims to increase co-operation among organisations involved in the fight against heart disease. ➢ The National Heart Alliance includes representation from a wide range of
National Heart Alliance
core