Results 61 to 70 of about 260,237 (259)

Primary Biatrial Cardiac Rhabdomyosarcoma

Brazilian Journal of Cardiovascular Surgery
Primary malignant neoplasms of the heart are rare. Cardiac rhabdomyosarcoma is the second most common primary sarcoma. We report a rare case of a 49-year-old woman with a huge biatrial cardiac rhabdomyosarcoma treated by performing surgical resection ...
Tetsuro Uchida, Yoshinori Kuroda, Mitsuaki Sadahiro   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

[Metastatic neoplasms of the heart].

Wiadomosci lekarskie (Warsaw, Poland : 1960), 1994
Two cases are presented of metastatic neoplasm of the heart easy for echocardiographic diagnosis. One infiltrated the pericardium with encapsulated fluid (visible also on X-ray), and the other was associated with filling of the right atrial lumen.
T, Petelenz, P, Knosała, B, Korzeniowska   +2 more
openaire   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Cardiac Myxoma

Autopsy and Case Reports, 2016
Primary cardiac tumors (PCT) are rare, accounting for 0.0017-0.03% in autopsy series,1,2 in contrast to metastatic tumors of the heart, which are 30 times more frequent.3,4 Nearly 75% of PCT are benign and most often represented by a myxoma in 50% of ...
Vera Demarchi Aiello, Fernando Peixoto Ferraz de Campos   +1 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Hodgkin lymphoma as a rare cause of complete atrioventricular block: a case report

КардиоСоматика
INTRODUCTION: Complete atrioventricular block is a life-threatening condition that requires urgent intervention and pacemaker implantation. Determining the underlying cause of the block is essential for effective management. This article describes a rare
Ekaterina A. Pravkina, Dmitry S. Sinitsyn, Polina S. Vikulova, Ilya B. Glukhovets, Sergei V. Subbotin   +4 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Case Report: A case of right ventricular metastasis from cervical cancer presenting with thrombocytopenia: the role of echocardiography and myocardial contrast echocardiography

Frontiers in Oncology
BackgroundCardiac metastasis from cervical cancer is rare and often presents with nonspecific symptoms, leading to diagnostic delays. This case highlights the role of myocardial contrast echocardiography (MCE) in detecting such metastases in long-term ...
Qian Yang, Dong Bai, Liming Bao, Lei Liang, Haijun Hou   +4 more
doaj   +1 more source