Results 81 to 90 of about 2,466,541 (396)

Primary cardiac neoplasms: do effective treatments exist [PDF]

, 2016
Primary cardiac neoplasms (PCNs) represent the rarest form of neoplastic growths worldwide with an incidence ranging from 0.001 - 0.3% in autopsy series (Yu et al., 2014) ("Primary Cardiac Neoplasms," 2014).
Noel, Vanesa Barbara
core   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Are Recessions Harmful to Health After All? Evidence from the European Union [PDF]

, 2007
This paper investigates the effects of national unemployment rates on overall age and cause-specific mortality rates in a panel sample of 13 European Union countries.
Economou, Athina, Nikolaou, Agelike, Theodossiou, Ioannis   +2 more
core  

Bibliometrics of systematic reviews : analysis of citation rates and journal impact factors [PDF]

, 2013
Background: Systematic reviews are important for informing clinical practice and health policy. The aim of this study was to examine the bibliometrics of systematic reviews and to determine the amount of variance in citations predicted by the journal ...
A Delaney, A Laupacis, A Liberati, AR Weale, AV Kulkarni, C Lokker, D Moher, DL Willis, E Evangelou, EE van der Wall, EJS Sonuga-Barke, GN Pierce, H Bastian, HF Moed, J Yaffe, K Okike, KC Siontis, L Colledge, L Pagliaro, M Bhandari, M Callaham, M Petticrew, ME Falagas, MH Johnson, NA Patsopoulos, PO Seglen, R Badgett, RJ McKinlay, S Winnik, T Greenhalgh, T Opthof, U Waheed, V Allareddy, VM Montori, WD Figg   +34 more
core   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Neutrophil-to-lymphocyte ratio is a novel predictor of venous thrombosis in polycythemia vera

Blood Cancer Journal, 2022
We investigated the neutrophil-to-lymphocyte ratio (NLR) as a predictor of thrombosis in polycythemia vera (PV). After a median follow-up of 2.51 years, of 1508 PV patients enrolled in the ECLAP study, 82 and 84 developed arterial and venous thrombosis ...
Alessandra Carobbio, Alessandro Maria Vannucchi, Valerio De Stefano, Arianna Masciulli, Paola Guglielmelli, Giuseppe Gaetano Loscocco, Francesco Ramundo, Elena Rossi, Yogendra Kanthi, Ayalew Tefferi, Tiziano Barbui   +10 more
doaj   +1 more source

Cancer incidence in British vegetarians [PDF]

, 2009
Background: Few prospective studies have examined cancer incidence among vegetarians. Methods: We studied 61 566 British men and women, comprising 32 403 meat eaters, 8562 non-meat eaters who did eat fish ('fish eaters') and 20 601 vegetarians.
AJ Cross, AJ Cross, D Forman, DD Alexander, DS Michaud, E A Spencer, EF Taylor, GE Fraser, GK Davey, J I Mann, JM Chan, M Schulz, M Thorogood, M Thorogood, MA Sanjoaquin, N E Allen, P N Appleby, PN Appleby, R C Travis, R García-Closas, RC Travis, S Zhang, T J Key, TJ Key, TJ Key, W Lijinsky   +25 more
core   +2 more sources

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Ranking Risk Inequities [PDF]

, 1995
Comparing recent data on age-adjusted death rates for blacks and whites, the authors attempt to clarify how ranking risks based on degree of inequity might differ from ranking them according to frequency of health impairments in the overall population ...
Graham, John D., Richardson, Elizabeth
core   +2 more sources