Results 1 to 10 of about 41,257 (268)

Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line

open access: yeseLife, 2023
Unlike single-gene mutations leading to Mendelian conditions, common human diseases are likely to be emergent phenomena arising from multilayer, multiscale, and highly interconnected interactions. Atrial and ventricular septal defects are the most common
Mahdi Moradi Marjaneh   +14 more
doaj   +1 more source

THE Epidemology of down’s syndrome among congential heart disease children in Faisalabad

open access: yesEuropean Journal of Volunteering and Community-Based Projects, 2021
Patients with Down’s syndrome are prone to have congenital heart defects. This study was conducted to evaluate the frequency of various congenital heart defects in children with Down’s syndrome.
Abdul Maajid Khokhar   +3 more
doaj   +2 more sources

Generation of a TBX5 homozygous knockout embryonic stem cell line (WAe009-A-45) by CRISPR/Cas9 genome editing

open access: yesStem Cell Research, 2021
Holt-Oram syndrome (HOS), which is caused by genetic changes in the TBX5 gene, affects the hands and heart. HOS patients have heart defects, including atrial septal defects (ASD), ventricular septal defects (VSD) and heart conduction disease.
Tiantian Zhao   +4 more
doaj   +1 more source

Non symptomatic atrial septal defect venosus type IVC – SV coexistent with non-obstructed foramen ovale in 78 years old patient – a case report

open access: yesJournal of Education, Health and Sport, 2017
Atrial septal defect may be seen under few forms. The most common is ASD secundarum – about 70% of defects. Coexistent non-obstructed foramen ovale with atrial septal defect venosus type IVC – SV is very rare.
Weronika Sandra Topyła   +4 more
doaj   +3 more sources

The role of three-dimensional transesophageal echocardiography in preoperative assessment of atrial septal defects

open access: yesПатология кровообращения и кардиохирургия, 2015
An atrial septal defect is the most common congenital heart disease. Transcatheter defect closure has become widespread in recent times and the requirements for this procedure are rather strict.
Д. Г. Тарасов   +2 more
doaj   +1 more source

Iatrogenic Atrial Septal Defect After MitraClip Transcatheter Edge-to-Edge Repair: To Close or Not to Close? [PDF]

open access: yesTexas Heart Institute Journal
The evolution of percutaneous procedures that use transseptal puncture to treat left-sided structural heart disease has led to the emergence of iatrogenic atrial septal defects as a potential complication.
Mariem Abdelsalam, MD   +3 more
doaj   +1 more source

Echocardiographic Evaluation of Atrial Septal Defect

open access: yesJournal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2020
Atrial septal defect accounts for 8-10% of all congenital heart defects. Echocardiography is method of choice for assessment of patient with a known or suspected atrial septal defect.
Sushil Azad
doaj   +1 more source

Holt-Oram Syndrome in Adult Presenting with Heart Failure: A Rare Presentation

open access: yesCase Reports in Cardiology, 2014
Holt-Oram syndrome is a rare inherited disorder involving the hands, arms, and the heart. The defects involve carpal bones of the wrist and the thumb and the associated cardiac anomalies like atrial or ventricular septal defects.
Rupesh Kumar   +7 more
doaj   +1 more source

Prevalence of congenital septal defects among congenital heart defect patients in East Africa: A systematic review and meta-analysis.

open access: yesPLoS ONE, 2021
IntroductionCongenital heart defects (CHDs) are the most common congenital defects and accounts for nearly one-third of all major congenital anomalies. It is the leading causes of birth defect-associated morbidity, mortality, and medical expenditures. Of
Yossef Teshome Zikarg   +2 more
doaj   +1 more source

Atrial septal defect with a rare occupying lesion in heart

open access: yesBMC Cardiovascular Disorders, 2022
Abstract Background Cardiac epicardium hemangiomas are exceedingly rare; however, they can cause significant hemodynamic impairment and large pericardial effusions. On rare occasion, cardiac tumors coexist with malformations of the heart.
Jinlan Chen   +5 more
openaire   +3 more sources

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