Results 141 to 150 of about 53,129 (300)

The HRAS Variant c.175G>A (p.Ala59Thr) Causes a Predominantly Ectodermal Phenotype Lacking Classic Costello Syndrome Features

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 407-418, February 2026.
ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen, Eveliina Brandt, Kaisa Kettunen, Outi Elomaa, Sirpa Kivirikko, Leila Jeskanen, Katriina Lappalainen, Nelli Sjöblom, Juha Kere, Katariina Hannula‐Jouppi, Liisa Harjama   +10 more
wiley   +1 more source

Successful Catheter‐Directed Thrombolysis for a Patient With Intermediate‐High‐Risk Pulmonary Embolism: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Acute pulmonary embolism (PE) is a prevalent cardiovascular condition with significant mortality and morbidity. Treatment strategies vary according to risk stratification. While anticoagulation is sufficient for low‐risk patients, high‐risk cases often necessitate systemic thrombolysis (ST) or surgical embolectomy.
Mohammadreza Motazedian, Ahoura Salehi Nowbandegani, Zahra Mohammadi, Sina Bazmi   +3 more
wiley   +1 more source

Retrospective Review of Perioperative Neonatal Echocardiography for Non‐Cardiac Surgery at a Quaternary Level Academic Hospital in Johannesburg, South Africa

Pediatric Anesthesia, EarlyView.
Bronwyn Faith Krause, Firoza Motara, Zainub Jooma   +2 more
wiley   +1 more source

Patient‐Specific Lumped‐Parameter Model for Quantifying Vessel‐Specific Remodeling and Predicting Right Ventricular Function in Pulmonary Hypertension

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Personalized, patient‐specific biophysical model enabling mechanistic assessment of right ventricular (RV) function as well as robust differentiation of pulmonary hypertension (PH) subtype from routine clinical measurements of pulmonary arterial pressure and flow.
Christopher G. Lechuga, Amirreza Kachabi, Mitchel J. Colebank, Claudia E. Korcarz, Farhan Raza, Naomi C. Chesler   +5 more
wiley   +1 more source

Heyde Syndrome: A Literature Review

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Heyde syndrome, a triad of anemia from gastrointestinal (GI) bleeding, aortic valve stenosis, and acquired von Willebrand syndrome, primarily affects individuals over 65. Management requires a multidisciplinary approach, including medical therapy, endoscopic intervention, and valve replacement.
Yashika Gupta, Abdul Rehman Shahid Khan, Viraj Shetty, Yeshwini Murali Krishna, Ayisha Maqsood, Muhammad Husnain Ahmad, Masab Ali, Betsy Samuel, Ali Gohar, Abdul Waheed, Muhammad Bilal Afzal, Rehan Naseer Ahmad, Saqib Maqsood   +12 more
wiley   +1 more source

Complex congenital heart and lung defects as a cause of hydrops fetalis in French bulldogs –micro-CT with contrast study

Scientific Reports
Limited data are available on the causes of hydrops fetalis in dogs. Congenital heart defects may be an important contributing factor. Standard autopsy often fails to provide a comprehensive and accurate diagnosis on very small hearts.
Olga Szaluś-Jordanow, Karolina Barszcz, Wojciech Mądry, Michał Buczyński, Michał Czopowicz, Adam Gierulski, Agata Moroz-Fik, Zofia Nowek, Marcin Mickiewicz, Michał Grzegorczyk, Jakub Jaroszewicz, Sylwia Tarka, Tomasz Stępień, Wojciech Święszkowski   +13 more
doaj   +1 more source

3D Whole‐Heart Joint T1/T1ρ Mapping and Water‐Fat Imaging on a Clinical 0.55‐T Low‐Field Scanner

NMR in Biomedicine, Volume 39, Issue 2, February 2026.
A 3D joint T1/T1ρ$$ \rho $$ mapping sequence was proposed at 0.55 T. Four interleaved T1 and T1ρ$$ \rho $$ encoded 3D volumes are acquired; images are reconstructed with nonrigid respiratory motion‐correction, low‐rank patch‐based denoising (HD‐PROST) and water‐fat separation; and T1/T1ρ$$ \rho $$ maps are estimated through dictionary matching.
Michael G. Crabb, Karl P. Kunze, Carlos Castillo‐Passi, Dongyue Si, Simon J. Littlewood, Claudia Prieto, René M. Botnar   +6 more
wiley   +1 more source

Determining Preclinical Safety of Aclarubicin in Pediatric Malignancies

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Anthracyclines are among the most effective chemotherapeutic agents used to treat pediatric malignancies. However, their clinical use is limited by dose‐dependent toxicities, particularly cardiotoxicity and secondary malignancies.
Darleen S. Tu, Aaron K. Olson, Kimberly S. Waggie, Nicolas M. Garcia, Virginia J. Hoglund, Stephanie I. Walter, Jenna R. Rosinski, Harini Sadeeshkumar, Radhika Patel, Erolcan Sayar, Michael C. Haffner, Lisa Maves, Jacques Neefjes, Jay F. Sarthy, Elizabeth R. Lawlor, Shireen S. Ganapathi   +15 more
wiley   +1 more source

358 Ventricular septal defect - not only congenital heart disease [PDF]

European Journal of Echocardiography, 2003
M KONKA, P HOFFMAN
openaire   +1 more source

Extrasystoles on 24‐h Holter Monitoring During the First Year of Life

Acta Paediatrica, Volume 115, Issue 2, Page 370-377, February 2026.
ABSTRACT Aim To assess the natural course of extrasystoles and their association with tachyarrhythmias on 24‐h Holter monitoring during the first year of life. Methods A retrospective chart review was performed among newborns referred for 24‐h Holter monitoring at Tampere University Hospital from 2011 to 2017.
Asta Uusitalo, Päivi H. Korhonen, Antti Tikkakoski, Pieta Lehtinen, Kaisa Ylänen, Tuija Poutanen   +5 more
wiley   +1 more source