Results 181 to 190 of about 65,471 (356)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Totally Endoscopic Robotic Atrial Septal Defect Repair on the Beating Heart

, 2010
Changqing Gao, Ming Yang, Gang Wang, Jiali Wang, Cangsong Xiao, Yang Wu, Jiachun Li   +6 more
openalex   +1 more source

Dietary Choline Intake During Pregnancy and Congenital Heart Defects in a Chinese Population. [PDF]

Nutrients
Li YH, Xiao Z, Guo R, Rekemubieke B, Hu W, Liu X, Yang J.   +6 more
europepmc   +1 more source

A comparison of high thoracic epidural anaesthesia versus conventional intravenous opioids in pediatric patients undergoing corrective open heart surgery for ventricular septal defect

, 2021
Kshetrimayum Sandeep Kumar Singh, Vipul Sharma, Sachin Shouche, Shibu Sasidharan, Harpreet S. Dhillon   +4 more
openalex   +2 more sources

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Autopsy cases of aortic dissection, myxomatous valve degeneration, and ventricular septal defect in pet minipigs. [PDF]

J Vet Diagn Invest
Ueda K, Nakamura SI, Kutara K, Ueda A, Ozaki K.   +4 more
europepmc   +1 more source

Phenotypic and molecular characterisation of CDK13-related congenital heart defects, dysmorphic facial features and intellectual developmental disorders [PDF]

, 2017
Andrews, Marisa V, et al,, Grange, Dorothy K   +2 more
core   +2 more sources

Atrial septal defects: Pattern, clinical profile, surgical techniques and outcome at Innova heart hospital: A 4-year review

, 2014
Daberechi K Adiele, IjeomaO Arodiwe, JosephatM Chinawa, JohnC Eze, V Gouthami, Murthy Ks, Egbuna Obidike, Fortune Ujunwa   +7 more
openalex   +1 more source

Cardiac Magnetic Resonance Imaging Findings and Evaluation of Heart Functions in Atrial Septal Defect Patients

, 2022
Sedat Altay, Murat Yoğurtçu, Onur Kaan AKKUŞ, Muhsin Engin ULUÇ   +3 more
openalex   +1 more source