Results 71 to 80 of about 2,286,837 (350)

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma   +15 more
wiley   +1 more source

Influence of Football on Physiological Cardiac Indexes in Professional and Young Athletes

open access: yesFrontiers in Physiology, 2018
Background: After long-term intensive training, considerable morphological and functional heart changes occur in professional athletes. Such changes arise progressively and regress upon interruption of the physical activity.
Cristian V. Francavilla   +17 more
doaj   +1 more source

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo   +13 more
wiley   +1 more source

The inferior caval vein draining into the left atrial cavity : a rare case [PDF]

open access: yes, 2011
The inferior vena cava (IVC) draining into the left atrium (LA) is exceedingly rare in the setting of the usual atrial arrangement (situs solitus).
McCarthy, Karen   +4 more
core  

A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]

open access: yes, 2013
Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo   +15 more
core   +3 more sources

Halide‐Exchange Arrest Enables Reabsorption‐Free CsPbCl3/CsPbI3 Perovskite Core/Shell Nanocrystals

open access: yesAdvanced Science, EarlyView.
Achieving large Stokes shifts in perovskite nanocrystals is challenging due to halide mobility that disrupts stable core–shell structures. Using CdCl2 passivation, this work stabilizes CsPbCl3/CsPbI3 heterostructures, yielding a ≈1.2 eV Stokes shift, high quantum yield, and fast exciton transfer, enabling reabsorption‐free emitters for advanced ...
Hiba H. Karakkal   +13 more
wiley   +1 more source

Large Cardiac Hydatidosis Bulging As a Mass to Pericardium-Case Report

open access: yesIranian Journal of Parasitology, 2015
A 47-year-old man presented as a dyspnea and fatigue. A transthoracic echocardi-ography (TTE) performed to assess valvar heart disease and left ventricular (LV) function showed a large hydatid cysts in the inter ventricular septum bulging to posterior of
Freidoun Sabzi   +4 more
doaj  

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]

open access: yes, 2015
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC   +5 more
core   +2 more sources

Overcoming PEG Antigenicity: Statistical PEG Isomers Reduce Antibody Binding

open access: yesAdvanced Science, EarlyView.
Conventional poly(ethylene glycol) (PEG) is commonly applied in biomedicine, but is now known to induce antibody formation. Here, it is shown that the development of “randomized PEG” (rPEG) featuring glycidyl methyl ether (GME) comonomers decreased antibody binding.
Mareike Deuker   +5 more
wiley   +1 more source

Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]

open access: yes, 2017
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana   +7 more
core   +1 more source

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