Results 91 to 100 of about 3,079,923 (316)
Advanced Science, EarlyView.Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei +15 more
wiley +1 more source
DIAGNOSIS OF ARRHYTHMIA DISEASES USING HEART SOUNDS AND ECG SIGNALS
Российский кардиологический журнал, 2014 This paper presents a novel method for the detection of Arrhythmia diseases using both heart sounds and ECG signals. This automated classification and analysis system is aimed to assist the cardiologist to make the diagnosis faster and more efficient ...
V. Kalaivani
doaj +1 more source
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
Advanced Science, EarlyView.In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao +12 more
wiley +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, EarlyView.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu +5 more
wiley +1 more source
Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, EarlyView.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Secondary Electron Hyperspectral Imaging of Carbons: New Insights and Good Practice Guide
Advanced Science, EarlyView.Secondary hyperspectral imaging of carbon surfaces is assessed with reference materials and in comparison to standard spectroscopies. Characterization of functional carbon materials from battery research reveals otherwise inaccessible information about the distribution of sp2 and amorphous carbon, as shown in graphite anode and carbon coated lithium ...
James F. Nohl +22 more
wiley +1 more source
Nature and Science of SleepMuammar M Kabir,1,2,* Atousa Assadi,1– 3,* Shumit Saha,4 Bojan Gavrilovic,1 Kaiyin Zhu,1 Susanna Mak,5 Azadeh Yadollahi1,2 1KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada; 2Institute for Biomedical ...
Kabir MM +6 more
doaj
Assessing hearing by measuring heartbeat: The effect of sound level.
PLoS ONE, 2019 Functional near-infrared spectroscopy (fNIRS) is a non-invasive brain imaging technique that measures changes in oxygenated and de-oxygenated hemoglobin concentration and can provide a measure of brain activity.
Mehrnaz Shoushtarian +3 more
doaj +1 more source
Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy
Advanced Science, EarlyView.As an inevitable disease, muscle atrophy has received more attention. Because the factors that induce this disease are diverse, achieving a complete cure is still impossible. Wearable bioelectronics provides a more comfortable, low‐cost, and efficient way of home care for the monitoring and treatment of muscle atrophy. Therefore, this review summarizes
Shuai Zhang +4 more
wiley +1 more source