Results 121 to 130 of about 3,369,116 (395)
Reinnervation post-heart transplantation.
European Heart Journal, 2017 Heart transplantation results in complete denervation of the donor heart with loss of afferent and efferent nerve connections. The majority of patients remain completely denervated during the first 6-12 months following transplantation.
A. Grupper, H. Gewirtz, S. Kushwaha
semanticscholar +1 more source
Normalization of high pulmonary vascular resistance with LVAD support in heart transplantation candidates [PDF]
, 2017 Objective: Pulmonary hypertension (PH) and elevated pulmonary vascular resistance (PVR) lead to poor outcome after heart transplantation due to postoperative failure of the non-conditioned right ventricle.
Lachat, Mario L. +4 more
core
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
Advanced Healthcare Materials, EarlyView.This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla +16 more
wiley +1 more source
, 2014 An artificial heart is a device that replaces the heart. Artificial hearts are typically used to bridge the time to heart transplantation, or to permanently replace the heart in case heart transplantation is impossible.
Nishta, B.V.
core
Unraveling the Role of Allo-Antibodies and Transplant Injury. [PDF]
, 2016 Alloimmunity driving rejection in the context of solid organ transplantation can be grossly divided into mechanisms predominantly driven by either T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), though the co-existence of both ...
Matsuda, Yoshiko, Sarwal, Minnie M
core +2 more sources
Advanced Healthcare Materials, EarlyView.Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho +7 more
wiley +1 more source
The use of cyclosporin A and prednisone in cadaver kidney transplantation [PDF]
, 1980 Eighteen patients were treated with primary cadaveric renal transplantation using cyclosporin A therapy, and four more patients underwent cadaveric retransplantation.
Iwaki, Y +8 more
core
Integration of Bioengineered Tools in Assisted Reproductive Technologies
Advanced Healthcare Materials, EarlyView.A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak +3 more
wiley +1 more source