Results 121 to 130 of about 2,071,977 (304)

Global disparities in access to cardiac care for congenital heart disease in low- and middle-income countries: A bibliometric analysis

open access: yesHeart Vessels and Transplantation
Objective: The aim of the study was to conduct a comprehensive bibliometric analysis of publications on inequalities in access to cardiac surgical care for congenital heart defects in order to systematize knowledge, identify the main research areas and ...
Irina Akhmedova   +2 more
doaj   +1 more source

Allosensitization and outcomes in pediatric heart transplantation

open access: yes, 2011
Allosensitization among children being considered for heart transplantation remains a great challenge. Controversy exists as to the best approach for those with elevated panel-reactive antibody (PRA) titers.
Rusconi, Paolo   +13 more
core   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

open access: yesAdvanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen   +5 more
wiley   +1 more source

Corrigendum to “Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation”

open access: yesStem Cells International, 2022
Imelda Ontoria-Oviedo   +10 more
doaj   +1 more source

Correlations between intraparenchymal cerebral temperature and peripheral temperature monitoring sites during rewarming after deep hypothermic circulatory arrest on cardiopulmonary bypass

open access: yesBMC Surgery
Background Optimal anatomical sites for temperature monitoring that most closely correlates with cerebral temperature remain debated in cardiac surgery, particularly during cardiopulmonary bypass (CPB) with deep hypothermic circulatory arrest (DHCA) and ...
Damien Parmantier   +19 more
doaj   +1 more source

Case Report: Low-profile covered stents in CHD: the role of Gore Viabahn (VBX) stents

open access: yesFrontiers in Pediatrics
The Gore Viabahn covered stent, approved for the treatment of peripheral arterial disease in femoral or iliac artery lesions, may offer advantageous features in the field of congenital heart diseases.
Micol Rebonato   +4 more
doaj   +1 more source

Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis

open access: yesAdvanced Science, EarlyView.
Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang   +9 more
wiley   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

open access: yesAdvanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin   +7 more
wiley   +1 more source

Early impact of CytoSorb® adsorber on proinflammatory cytokine plasmatic levels in a porcine model of refractory cardiogenic shock supported with VA-ECMO

open access: yesBMC Cardiovascular Disorders
Background Cardiogenic shock (CS) is a pejorative situation which often requires a circulatory support with VA-ECMO. However, VA-ECMO is known to trigger an inflammatory cascade with expression of proinflammatory cytokines Interleukin-6 (IL-6) and ...
Juliette Piccoli   +9 more
doaj   +1 more source

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