Results 161 to 170 of about 418,657 (362)

Clearance of passenger blood cells as an adjunct in decreasing rejection in canine heterotopic heart transplants

open access: bronze, 1974
Lorenzo González-Lavin   +4 more
openalex   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao   +20 more
wiley   +1 more source

Changes in coronary blood flow during rejection of the orthotopically transplanted canine heart

open access: bronze, 1972
Edward B. Stinson   +3 more
openalex   +1 more source

Resident Macrophage‐Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor‐Associated Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma   +11 more
wiley   +1 more source

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi   +9 more
wiley   +1 more source

A Resistive Soft Robotic Exosuit for Dynamic Body Loading in Hypogravity

open access: yesAdvanced Science, EarlyView.
The resistive hypogravity exosuit is a lightweight wearable robotic exosuit that uses pneumatic artificial muscles to restore Earth‐like metabolic and muscular demands during locomotion in low gravity. Tested on healthy subjects in Earth and simulated Moon gravity, the suit restores energy expenditure and muscle activation without altering gait ...
Emanuele Pulvirenti   +6 more
wiley   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu   +13 more
wiley   +1 more source

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