Results 131 to 140 of about 3,672,098 (295)

Comparing outcomes using low‐dose apixaban and anti‐Xa monitoring and vitamin K antagonists in patients with renal replacement therapy

British Journal of Clinical Pharmacology, EarlyView.
Background Guidelines recommend oral anticoagulation for stroke prevention in atrial fibrillation and secondary prevention of venous thromboembolism. Outside the United States, apixaban is unlicensed for use in patients with end‐stage renal disease (ESRD) receiving renal replacement therapy (RRT).
John K. Bartoli‐Abdou, Alexander T. Cohen, Lucy Vernon, Victoria Collings, Ubonphan Chaichana, Natasha Moore, Hamda Jibril, Li Wei, Nicola Kumar, Karen A. Breen, Andrew J. Doyle   +10 more
wiley   +1 more source

Transcatheter and Surgical Approaches to Addressing the Complications of Transcatheter Procedures: Current Trends and Future Challenges

Journal of Cardiovascular Development and Disease
Transcatheter structural heart procedures, including transcatheter aortic valve replacement (TAVR) and transcatheter edge-to-edge repair (TEER), have revolutionized the management of valvular heart diseases in selected or high-risk patients [...]
Antonio Nenna, Giovanni Casali, Giuseppe Patti, Carmelo Dominici   +3 more
doaj   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Purification and concentration of model viruses using single‐pass tangential flow filtration

Biotechnology Progress, EarlyView.
Single‐pass TFF was developed for an enveloped and non‐enveloped virus for use in continuous downstream purification processes. Enveloped virus was concentrated and purified. Abstract The vaccine and viral vector industry is growing at an accelerated rate.
Luis Alberto Mejía‐Manzano, Lynn Manchester, Grace Wallis, Kan Wang, Bruce P. Lee, Michael Betenbaugh, Caryn L. Heldt   +6 more
wiley   +1 more source

Design criteria for the trileaflet mechanical heart valve

, 2010
碩士本研究的目的是設計出一個理想的人工心瓣。雖然人工心瓣發展已經超過半個世紀，但目前臨床上所使用的機械心瓣還是存在血栓與溶血等缺點，而生物心瓣卻有不耐用的問題。本文利用分析各種三葉片機械心瓣的專利和相關文獻，進而提出全新的改良設計。新設計的葉片與環座是完全以自由曲面所建構而成，外形平順完整而沒有突出的支架，具有圓滑的轉軸，使葉片能夠靈活地轉動。 然後以鈦合金製作實驗原型，提供實驗團隊進行體外流場實驗分析，以驗證新設計的流場性能表現與發展可行性。然後根據新設計的概念，提出美國專利申請 ...
黃仁宏; Huang, Ren-hong
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Regenerative perfusion bioreactor for biologics production with lower COGs

Biotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne, Dohyun Park, Hourieh Ahi, Jaeweon Lee, Seongkyu Yoon, Jongyoon Han   +5 more
wiley   +1 more source

Successful Transcatheter Valve-in-Valve Implantation in a Small Deteriorated Aortic Valve Bioprosthesis

, 2013
Increased life expectancy and improvement in clinical outcome following surgery has led to an increasing number of elderly patients with a history of prior aortic valve replacement (AVR).
Bjursten, Henrik,, Harnek, Jan,, Nozohoor, Shahab,, Götberg, Matthias,, Lund University.   +4 more
core  

Clinical Anatomy of the Left and Right Atrial Appendages in Humans: Comparative and Developmental Perspective

Clinical Anatomy, EarlyView.
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová, Caroline Neradilová, Jan Kovanda, Jan Burkert, Jiří Beneš Jr., Martin Bartos, Theodor Adla, Vojtech Melenovsky, Alena Kvasilova, Ondrej Fabian, Ondrej Naňka, David Sedmera   +11 more
wiley   +1 more source

Efficacy and safety of mechanical pulmonary valve replacement: a comprehensive systematic review and meta-analysis

Journal of Cardiothoracic Surgery
Background Pulmonary valve replacement (PVR) is the most common valve replacement procedure for pulmonary valve dysfunction in congenital heart diseases (CHD).
Ali Rafati, Sina Rashedi, Yeganeh Pasebani, Milad Vahedinejad, Hamed Ghoshouni, Yaser Toloueitabar, Mostafa Mousavizadeh, Sedigheh Saedi, Amirhosein Jalali, Zahra Khajali, Hassan Tatari, Fahimeh Farrokhzadeh, Hooman Bakhshandeh, Maziar Gholampour Dehaki, Behshid Ghadrdoost, Parham Sadeghipour   +15 more
doaj   +1 more source

Ultrasound Phonocardiography for the Functional Assessment of Mechanical Heart Valves

, 2011
The main drawback of mechanical heart valves (MHVs) is possible thrombus formation, which reduces hemodynamic performances and increases embolic events. The present study describes an approach to the in vitro assessment of various thrombotic deposits on ...
PENGO, VITTORIO, SUSIN, FRANCESCA MARIA, GAGLIANO O, BOTTIO, TOMASO, BAGNO, ANDREA, TARZIA V, ROMATA C, GEROSA, GINO   +7 more
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