Results 71 to 80 of about 134,084 (261)

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

Advanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao, Xinyun Zhang, Qian Ren, Xue Song, Meifang Zhao, Rongshen Wang, Haocheng Du, Yan Chen, Peigen Xu, Jiangyun Liu, Jian Zhang, Jingjing Ma   +11 more
wiley   +1 more source

Editorial: Heart valve diseases: from molecular mechanisms to clinical implications. [PDF]

Front Mol Med, 2023
Ibarrola J, Lopez-Andres N.
europepmc   +1 more source

DUSP26 Regulated by YY1 Lactylation Couples Osteogenesis and Angiogenesis by Dephosphorylating PMPCB at Y141 and Activating Mitophagy in BMSCs

Advanced Science, EarlyView.
p300‐associated YY1 lactylation promotes DUSP26 expression in BMSCs. By regulating PMPCB phosphorylation and PINK1 processing, DUSP26 supports mitophagy, osteogenic differentiation, and pro‐angiogenic factor secretion. BMSC‐derived exosomes carrying a RUNX2 promoter‐driven DUSP26 plasmid favor osteogenic‐lineage transgene expression, partially ...
Yunpeng Lv, Feng Wu, Xiongjie Liang, Chong Liu, Wenhui Guo, Kejian Zhang, Jiawen Niu, Wenjie Jiang, Hongjian Xu, Anlong Jiang, Yang Zheng, Enming Yu, Xintao Wang, Jinglong Yan, Jingjun Xia, Chengchao Song   +15 more
wiley   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Diagnosis of mitral insufficiency using impedance cardiography technique ICG

Journal of Electrical Bioimpedance, 2016
Impedance cardiography (ICG) is a non-invasive tool for assessing the hemodynamic parameters. It has been used for diagnosing several cardiovascular diseases, such as heart failure, cardio-myopathy, and valvular diseases. Particularly, the valvular heart
Chabchoub Souhir, Mansouri Sofienne, Salah Ridha B.   +2 more
doaj   +1 more source

[Detection method of early heart valve diseases based on heart sound features]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2023
Sun C, Wang X, Liu C.
europepmc   +1 more source

Small Intestinal Bacterial Overgrowth Following Gastrointestinal Cancer Surgery: Current Evidence and Future Perspectives

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Small intestinal bacterial overgrowth (SIBO) has recently gained increasing attention as a potential cause of postoperative gastrointestinal symptoms following gastrointestinal cancer surgery. Surgical procedures can disrupt normal gastrointestinal physiology through anatomical reconstruction, impaired motility, reduced gastric acid secretion,
Toru Aoyama, Haruhiko Cho, Takaki Yoshikawa   +2 more
wiley   +1 more source

A Bioinspired Underwater Soft Robot for Active Intravesical Liquid Delivery and Mixing

Advanced Intelligent Systems, EarlyView.
A bioinspired underwater soft robot is reported that integrates an elastic strain energy‐driven soft robotic pump with a programmable flexible magnetic valve, enabling remotely controlled, programmable, and sustained liquid release and mixing. This functionality is enabled by the synergistic integration of elastic strain energy‐driven pumping and ...
Jacob Katona, Sage Bernstein, Boyang Xiao, Amie Zhang, Ellen Lu, Evan Ticknor, Jeffrey J. Tosoian, Xiaoguang Dong   +7 more
wiley   +1 more source

Value of the systemic immune-inflammation index in predicting poor postoperative outcomes and the short-term prognosis of heart valve diseases: a retrospective cohort study. [PDF]

BMJ Open, 2022
Xiang J, He L, Li D, Wei S, Wu Z.
europepmc   +1 more source

Development of an Inchworm‐Like Dual‐Balloon‐Assisted Colonoscopic Robot Based on a Two‐Segment Extensible Continuum Section

Advanced Intelligent Systems, EarlyView.
This work presents an inchworm‐like dual‐balloon‐assisted colonoscopic robot (IDCR) based on a rod‐driven two‐segment continuum section. The IDCR enables the active straightening of the sigmoid colon through an inchworm‐like locomotion strategy, thereby avoiding loop formation.
Dezhi Song, Bohan Leng, Yi Liu, Xiangyang Yu, Chaoyang Shi   +4 more
wiley   +1 more source