Results 81 to 90 of about 92,310 (290)

Diagnosis of mitral insufficiency using impedance cardiography technique ICG

Journal of Electrical Bioimpedance, 2016
Impedance cardiography (ICG) is a non-invasive tool for assessing the hemodynamic parameters. It has been used for diagnosing several cardiovascular diseases, such as heart failure, cardio-myopathy, and valvular diseases. Particularly, the valvular heart
Chabchoub Souhir, Mansouri Sofienne, Salah Ridha B.   +2 more
doaj   +1 more source

Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning

Advanced Science, EarlyView.
This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi, Nikhil Kadivar, Tanmay Mukherjee, Emilio A. Mendiola, Akila Bersali, Dipan J. Shah, George Karniadakis, Reza Avazmohammadi   +7 more
wiley   +1 more source

Bioprosthetic valve thrombosis in carcinoid heart disease

Annals of Cardiac Anaesthesia, 2019
Tricuspid regurgitation in carcinoid syndrome leads to significant morbidity and mortality that may warrant a tricuspid valve replacement. However, for patients with high serotonin levels and known hypercoagulable risks, the optimum timing for surgery and postoperative anticoagulation approaches remain unclear.
Brijen Joshi, Kimberly N. Hollander
openaire   +4 more sources

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

Advanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie, Tianyi Ji, Zixin Wan, Jie Huang, Han Li, Lingjiao Zou, Zhen Yang, Jiarui Li, Yuqi Guan, Lei Ruan, Jinhua Yan, Cuntai Zhang   +11 more
wiley   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source

Spectral analysis of heart valve sound for detection of prosthetic heart valve diseases

Yonsei Medical Journal, 1998
The spectral analysis of heart valve sound is a noninvasive diagnostic method known to be useful in evaluating the state of the heart valve function. This may provide early detection of valve calcification, thrombus or destruction, since previous studies have shown that the dominant frequency peak moved to a high frequency area when natural heart valve
Byung Chul Chang, Sang Hyun Kim, Hee Jong Lee, Jae Man Huh   +3 more
openaire   +4 more sources

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Percutaneous dual-valve intervention in a high-risk patient with severe aortic and mitral stenosis

Heart Views, 2016
Aortic stenosis is the most frequent and mitral stenosis is the least frequent native single-sided valve disease in Europe. Patients with the combination of severe symptomatic degenerative aortic and mitral stenosis are very rare.
Blaz Mrevlje, Mohamad Aboukura, Christoph A Nienaber   +2 more
doaj   +1 more source

Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency. [PDF]

, 1988
Edward D. Pagani, Adawia A. Alousi, Alison M. Grant, Thomas M. Older, Stanley W. Dziuban, Paul Allen   +5 more
openalex   +1 more source