Results 31 to 40 of about 33,296 (267)

Valvular Heart Disease and Its Association With Death in Advanced Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Valvular heart disease contributes to symptomatic heart failure, but its prevalence and prognostic significance in advanced heart failure is not well understood. Methods This retrospective population‐based cohort study included adult residents
Kyle G. Steiger, David M. Harmon, Jill M. Killian, Vuyisile T. Nkomo, Margaret Redfield, Shannon M. Dunlay   +5 more
doaj   +1 more source

Diagnosis of mitral insufficiency using impedance cardiography technique ICG

Journal of Electrical Bioimpedance, 2016
Impedance cardiography (ICG) is a non-invasive tool for assessing the hemodynamic parameters. It has been used for diagnosing several cardiovascular diseases, such as heart failure, cardio-myopathy, and valvular diseases. Particularly, the valvular heart
Chabchoub Souhir, Mansouri Sofienne, Salah Ridha B.   +2 more
doaj   +1 more source

Nitric oxide synthase-3 promotes embryonic development of atrioventricular valves. [PDF]

PLoS ONE, 2013
Nitric oxide synthase-3 (NOS3) has recently been shown to promote endothelial-to-mesenchymal transition (EndMT) in the developing atrioventricular (AV) canal.
Yin Liu, Xiangru Lu, Fu-Li Xiang, Man Lu, Qingping Feng   +4 more
doaj   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Improvement of Rheumatic Valvular Heart Disease in Patients Undergoing Prolonged Antibiotic Prophylaxis

Frontiers in Cardiovascular Medicine, 2021
Secondary prophylaxis of rheumatic heart diseases is efficient in reducing disease recurrence, heart damage, and cardiac impairment. We aimed to monitor the clinical evolution of a large Brazilian cohort of rheumatic patients under prolonged secondary ...
Renato Pedro de Almeida Torres, Rômulo Francisco de Almeida Torres, Gabrielle de Crombrugghe, Scarllet Palacin Moraes da Silva, Sarah Leticia Veroneze Cordeiro, Karine Alessandra Bosi, Pierre R. Smeesters, Pierre R. Smeesters, Pierre R. Smeesters, Pierre R. Smeesters, Rosângela Stadnick Lauth de Almeida Torres, Rosângela Stadnick Lauth de Almeida Torres   +11 more
doaj   +1 more source

Mitral Valve Repair in Children With Rheumatic Heart Disease [PDF]

ACC Current Journal Review, 2005
The purpose of this study was to assess the long-term results of mitral valve repair in children with chronic rheumatic heart disease.From January 1988 through December 2003, 278 children (153 male children) underwent mitral valve repair. Mean age was 11.7 +/- 2.9 years (range, 2-15 years).
Talwar, Sachin, Rajesh, Manithara Raman, Subramanian, Anandaraja, Saxena, Anita, Kumar, Arkalgud Sampath   +4 more
openaire   +2 more sources

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Combined mitral valve repair and heart transplantation

Clinical Case Reports, 2018
Key Clinical MessageIn times of donor organ shortage, organs with extended allocation criteria, for example, valve pathologies, have to be taken into consideration for transplantation. The donor pool can be extended to hearts with mitral valve insufficiency.
Anke Sprengel, Wojtek Skwara, Tibor Ziegelhöffer, Ayse Cetinkaya, Markus Schönburg, Manfred Richter   +5 more
openaire   +2 more sources

'Edge-to-edge' mitral valve repair: the ace of hearts [PDF]

European Heart Journal, 2006
A 32-year-old man underwent a successful surgical correction of a severe mitral regurgitation. The surgical procedure consisted of an ‘edge-to-edge’ repair of the valve, connecting the mid-portion of the anterior and posterior leaflets, associated with implantation of a mitral annuloplasty ring (Sovering O 38 mm; …
ZACÀ V., GIACOMIN E., CHIAVARELLI M., MONDILLO S.   +3 more
openaire   +4 more sources

Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen, Julia Riedesel, Juliane Stein, Brandon H. Greene, Svenja Rohde, Sonja Suess, Bjoern Keiner, Priya Panjwani, Padmapriya Ponnuswamy, Juan E. Camacho Londoño   +9 more
wiley   +1 more source