Results 51 to 60 of about 51,149 (311)

Mitral Valve Surgery in Advanced Heart Failure

Journal of the American College of Cardiology, 2010
The appropriateness and timing of mitral valve surgery in patients with advanced heart failure and severe mitral regurgitation remains controversial. Recent surgical results provide evidence for beneficial effects on left ventricular remodeling and functional capacity.
Di Salvo, Thomas G., Acker, Michael A., Dec, G. William, Byrne, John G.   +3 more
openaire   +2 more sources

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Plástica da valva mitral: resultados tardios de doze anos de experiência e evolução das técnicas Twelve years follow-up with mitral valve reconstruction

Brazilian Journal of Cardiovascular Surgery, 1994
Foram estudados 301 pacientes, sendo 151 (50,2%) do sexo masculino, com idade variando de 3 meses a 79 anos (média de 37,96 com desvio padrão de 21,4 anos).
Pablo M. A Pomerantzeff, Carlos M. A Brandão, Ana Cristina M Monteiro, Ana Carolina Nersessian, Antonio E Zeratti, Noedir A. G Stolf, Miguel Barbero-Marcial, Sérgio A Oliveira, Geraldo Verginelli, Adib D Jatene   +9 more
doaj  

On-pump fibrillating heart mitral valve replacement with the SAPIEN™ XT transcatheter heart valve [PDF]

, 2017
In some high-risk patients, standard mitral valve replacement can represent a challenging procedure, requiring a risky extensive decalcification of the annulus. In particular, high-risk redo patients and patients with a previously implanted transcatheter
Ferrari, Enrico, Locca, Didier, Marcucci, Carlo, Niclauss, Lars   +3 more
core  

Biological niches within human calcified aortic valves. Towards understanding of the pathological biomineralization process [PDF]

, 2015
Despite recent advances, mineralization site, its microarchitecture, and composition in calcific heart valve remain poorly understood. A multiscale investigation, using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ...
Cavarretta, Elena, Cottignoli, Valentina, Familiari, Giuseppe, Giovanna, Agrosì, Loris, Salvador, Maras, Adriana, Relucenti, Michela   +6 more
core   +3 more sources

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

The role of visual diagnostics in establishing the stages of development of mitral valve insufficiency in dogs [PDF]

E3S Web of Conferences
The aim of the work is to develop a scientifically based approach the established role of visual diagnostics in determining the stages of development of mitral valve insufficiency in dogs.
Kostylev Vladislav, Goncharova Anna, Shtaufen Alexandra   +2 more
doaj   +1 more source

Three-dimensional structure of the flow inside the left ventricle of the human heart

, 2013
The laboratory models of the human heart left ventricle developed in the last decades gave a valuable contribution to the comprehension of the role of the fluid dynamics in the cardiac function and to support the interpretation of the data obtained in ...
Cenedese, A., Espa, S., Fortini, S., Querzoli, G.   +3 more
core   +1 more source

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

AGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang, Yuan Xue, Yeting Lou, Hao Han, Xiaohan Zhong, Zhou Liu, Tianxu Han, Meili Wang, Wenjian Jiang, Hongjia Zhang, Haiyang Li, Yuanfei Zhao   +11 more
wiley   +1 more source

Dynamic three-dimensional reconstruction of the heart by transesophageal echocardiography

Arquivos Brasileiros de Cardiologia, 1999
OBJECTIVE: To evaluate echocardiography accuracy in performing and obtaining images for dynamical three-dimensional (3D) reconstruction. METHODS: Three-dimensional (3D) image reconstruction was obtained in 20 consecutive patients who underwent ...
Maria de Fátima Veiga, Mário G. Lopes, Fausto J. Pinto   +2 more
doaj   +1 more source