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Materials and manufacturing perspectives in engineering heart valves: a review
Valvular heart diseases (VHD) are a major health burden, affecting millions of people worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial heart valves including mechanical and bioprosthetic valves.
F. Oveissi +4 more
doaj +1 more source
Dynamic Views of Structure and Function during Heart Morphogenesis [PDF]
Congenital heart defects remain the most common birth defect in humans, occurring in over 1% of live births. The high prevalence of cardiac malformations can be partially attributed to limited knowledge regarding the embryonic roots of the disease.
Forouhar, Arian Soroush
core +1 more source
Background Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical use are associated with significant limitations.
Steve W. F. R. Waqanivavalagi +4 more
doaj +1 more source
Background: Polymeric heart valves (PHVs) may address the limitations of mechanical and tissue valves in the treatment of valvular heart disease. In this study, a bioinspired valve was designed, assessed in silico, and validated by an in vitro model to ...
Aeryne Lee, PhD +10 more
doaj +1 more source
Heart diseases caused by structure and function degradation is troubling millions of people all over the world. With the extension of human lifespan, the demand for heart valve replacement is rapidly increasing.
Ziyu Shao +10 more
doaj +1 more source
Aim. The aim of this review was to analyze publications describing studies focusing on the pathophysiological mechanisms of calcification of bioprosthetic heart valves, and to substantiate new and promising methods of calcification prevention for the ...
A. E. Kostyunin +3 more
doaj +1 more source
SUMMARY This paper summarizes the experience in the treatment of a series of 1,370 cases of open-heart surgery. Of these, 964 valvular lesions and the associated pathologic lesion are analyzed. Details of correction and immediate and late results in the treatment of the following groups of lesions were studied: 74 cases of congenital aortic stenosis ...
E J, ZERBINI +2 more
openaire +2 more sources
A Deep Learning Framework for Design and Analysis of Surgical Bioprosthetic Heart Valves
Bioprosthetic heart valves (BHVs) are commonly used as heart valve replacements but they are prone to fatigue failure; estimating their remaining life directly from medical images is difficult.
Aditya Balu +5 more
semanticscholar +1 more source
Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Annemijn Vis +14 more
doaj +1 more source
A parallel interaction potential approach coupled with the immersed boundary method for fully resolved simulations of deformable interfaces and membranes [PDF]
In this paper we show and discuss the use of a versatile interaction potential approach coupled with an immersed boundary method to simulate a variety of flows involving deformable bodies.
de Tullio, Marco D +6 more
core +3 more sources

