Results 111 to 120 of about 2,557,215 (346)

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

The effect of Endurance Exercise on myh6 Gene Expression and Structural and Functional Changes of Left Ventricular

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2016
Background and Objectives: Endurance exercise induces cardiac remodeling. Also, myh6 gene is affected by cardiac remodeling. This study was performed with the objective of determining the effect of endurance activity on cardiac myh6 gene expression ...
Mohammad Fathi
doaj  

Biaxial Testing of Cadaveric and Decellularized Rat Heart Ventricles

, 2011
Additional contributors: Colleen Witzenburg; Stefan Kren; Doris Taylor; Victor Barocas (faculty mentor)Whole organ decellularization is a promising technique to create 3D scaffolds necessary to generate bioartificial organs.
Vanderheiden, Sarah
core  

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Histological Characterization and Histochemical Profiling of the Heart of Prenatal Goat (Capra hircus)

International Journal of Bio-Resource and Stress Management
The study was conducted during July to October, 2020 at the Department of Veterinary Anatomy, College of Veterinary Science and Animal Husbandry, Nanaji Deshmukh Veterinary Science University, Jabalpur, Madhya Pradesh, India to investigate the ...
Raj Gayatri, J. S. Taluja, Rakhi Vaish, Nripendra Singh, Diksha Lade, Shashi Tekam, Shashi Bharti, Kajal Kumar Jadav   +7 more
doaj   +1 more source

The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease

, 2017
The Sydney Heart Bank (SHB) is one of the largest human heart tissue banks in existence. Its mission is to provide high-quality human heart tissue for research into the molecular basis of human heart failure by working collaboratively with experts in ...
W. Linke, Marston, S. B., C. G. dos Remedios, F. Pontén, van der Velden, J., J. Stelzer, R. Cooke, Pontén, F., J. McNamara, C. Bezzina, van Dijk, S., Li, A.,, P. S. Macdonald, S. van Dijk, G. J. M. Stienen, Keogh, A.,, Stelzer, J., Pontén, Fredrik,, Macdonald, P. S., Li, A., McNamara, J.,, Cooke, R., Lal, S. P., J. Odeberg, H. Granzier, De Man, F., Lal, S. P.,, McNamara, J., Keogh, A., dos Remedios, C. G., Linke, W., Granzier, H., dos Remedios, C. G.,, Stienen, G. J. M., S. B. Marston, F. De Man, J. van der Velden, Ehler, E., Bezzina, C., S. P. Lal, Odeberg, J., Stienen, G. J.M., A. Keogh, E. Ehler, A. Li, Knöll, R., R. Knöll   +46 more
core   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

An analysis of defibrillation and cardiac resynchronization therapy strategies in patients with failing systemic right ventricles

, 2007
Includes bibliographical references (leaves 52-56).The expanding application of cardiac resynchronization (CRT) and implantable cardioverter-defibrillator therapy (lCD) to include patients with congenital heart disease requires careful evaluation of ...
Michael, Kevin A
core  

Landmarks and lineages in the developing heart.

, 2009
Comment on The Tbx2+ primary myocardium of the atrioventricular canal forms the atrioventricular node and the base of the left ventricle. [Circ Res.
Harvey, Richard P, Meilhac, Sigolène M, Buckingham, Margaret E   +2 more
core   +1 more source