Results 121 to 130 of about 2,557,215 (346)

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Arrhythmogenic Cardiomyopathy with Biventricular Involvement and Right Ventricular Thrombosis: A Multi-modality Imaging Approach

Heart Views
Arrhythmogenic cardiomyopathy (AC) is an inherited heart disease characterized by fibro-fatty changes of either ventricles in isolation or in combination.
Fawaz Bardooli, Dhuha Rashed Aljawder, Dileep Kumar, Sadananda Padavagodu Shivappa, Anna Baritussio   +4 more
doaj   +1 more source

Improving the diagnosis of diastolic dysfunction of heart ventricles in newborns by tissue Doppler imaging

, 2017
in order to improve diagnosis of myocardial dysfunction of heart ventricles in newborns in the neonatal period the study implied administration of pulsed-wave tissue Doppler imaging with determination of diastolic dysfunction ...
Gonchar, Margaryta, Boichenko, А.
core  

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

Effects of Radiofrequency Ablation on the Epicardial Nerves in Experimental Sheep Heart Ventricles.

, 2017
Effects of Radiofrequency Ablation on the Epicardial Nerves in Experimental Sheep Heart Ventricles. Final Paper in the Program of Study in Medicine/ Academic Advisor: Dr.
Ivaškevičius, Linvydas
core  

Apamin Sensitive Potassium Current Modulates Action Potential Duration Restitution and Arrhythmogenesis of Failing Rabbit Ventricles

, 2013
Background: Apamin-sensitive K currents (I(KAS)) are upregulated in heart failure. We hypothesize that apamin can flatten action potential duration restitution (APDR) curve and can reduce ventricular fibrillation duration in failing ventricles.
Chen, Zhenhui, Lin, Shien-Fong, Hsieh, Yu-Cheng, Shen, Changyu, Chen, Peng-Sheng, Weiss, James N., Ai, Tomohiko, Lee, Young Soo, Chang, Po-Cheng, Hsueh, Chia-Hsiang   +9 more
core   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Taquicardia ventricular en miocardiopatía no compactada

Revista Ciencias Biomédicas, 2013
Introduction: left ventricular noncompaction (LVNC) is a rare disease with genetic origin, characterized by the presence of numerous myocardial trabeculations probably due to a detention of the normal process of the endomyocardial embryogenesis ...
García-Torres Edinson, Cordero-Díaz Luis, Corrales-Santander Hugo   +2 more
doaj  

Specialized impulse conduction pathway in the alligator heart

, 2018
Mammals and birds have a specialized cardiac atrioventricular conduction system enabling rapid activation of both ventricles. This system may have evolved together with high heart rates to support their endothermic state (warm-bloodedness) and is ...
Boukens, Bastiaan J, Postma, Alex V, Elsey, Ruth M, Mohan, Rajiv A, Gloschat, Christopher R, van Duijvenboden, Karel, Sedmera, David, Crossley, Dane A, Efimov, Igor R, Jensen, Bjarke, Conner, Justin, Christoffels, Vincent M   +11 more
core   +1 more source

Connexin 43‐Enriched Vesicles Improve Synchronization in hiPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Plasma membrane‐derived Connectosomes enriched in connexin‐43 are produced from donor hiPSCs and applied to hiPSC‐derived cardiomyocytes (hiPSC‐CMs). Connexin‐43 channels on Connectosomes remain functional, strengthening intercellular electrochemical coupling and increasing network synchronization over time.
Nima Momtahan, Anna K. McClain, Andrea Trementozzi, Sogu Sohn, Lingxia Qiao, Chi Zhao, Padmini Rangamani, Jeanne C. Stachowiak, Janet Zoldan   +8 more
wiley   +1 more source