Results 121 to 130 of about 85,595 (264)

A computational framework for modeling fluid and solid stresses in porous tissues with application to the trabeculated embryonic heart. [PDF]

PLoS Comput Biol
Buffinton CM, Baish JW.
europepmc   +1 more source

Case of Rupture of the Left Ventricle of the Heart [PDF]

BMJ
openaire   +2 more sources

Macrophage GLUD1 is Essential for Redox Balance and Immune Homeostasis in Cardiac Injury

Advanced Science, EarlyView.
Excessive free radical production and dysregulated immune responses are key contributors to myocardial ischemia‐reperfusion (IR) injury. Macrophage GLUD1 activity safeguards against HIF‐1α accumulation and maladaptive responses to IR‐induced ROS production.
Tingting Jin, Chaojie Lai, Qingyan Zhou, Ruilin Wang, Yiping Tong, Wentao Chen, Nikola Rabrenovic, Tingyu Zhang, Xinrong Ren, Chengchen Huang, Jiawen Chen, Ran Li, Luyang Yu, Massimiliano Mazzone, Wenbin Zhang, Guosheng Fu, Min Shang   +16 more
wiley   +1 more source

The 'Upstairs-Downstairs' heart with complete main pulmonary artery agenesis and PDA-dependent pulmonary circulation: A rare structural intersection characterized by multi detector computed tomography. [PDF]

Radiol Case Rep
Kanji AM, Aziz T, Fundikira L, Akberali U, Salingwa L, Lyimo F, Jacob M.   +6 more
europepmc   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Biventricular endomyocardial fibrosis with right ventricular hypertrabeculation and rapid progression to heart transplantation: imaging and pathologic correlation. [PDF]

Einstein (Sao Paulo)
Faustino SAF, Rodrigues ACT, Oliveira EC, Azevedo J, Sakamoto FH, Fischer CH, Mangini S, Lira-Filho E, Morhy SS, Mocumbi AOH, Vieira MLC.   +10 more
europepmc   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Adma and Ackr3a regulate cardiac lymphatic vessel formation and function during heart development and regeneration. [PDF]

Nat Commun
Feng X, Chen HY, Sun Y, Sun F, Yan S, Kapuria S, Rodriguez R, Gamba L, Crump JG, Hong YK, Poss KD, Lien CL.   +11 more
europepmc   +1 more source

SPONTANEOUS RUPTURE OF THE RIGHT VENTRICLE OF THE HEART [PDF]

BMJ, 1927
openaire   +2 more sources

Melatonin Mitigates Doxorubicin‐Induced Cardiotoxicity by Targeting the USP18/PKM2 Axis Without Compromising Antitumor Efficacy

Advanced Science, EarlyView.
Melatonin engages MT1/MT2 receptors to suppress STAT1‐driven USP18 upregulation, thereby redirecting PKM2 ubiquitination from K33‐linked autophagic degradation toward K27‐linked nuclear translocation. This prevents PKM2‐mediated proinflammatory gene expression in the heart, alleviating doxorubicin‐induced cardiotoxicity without compromising antitumor ...
Zhenyu Feng, Yijin Yang, Jie Bai, Pengqi Sun, Xuyang Sun, Jinshu Shang, Yang Liu, Zhen Ning, Ningning Zhang, Yun‐long Xia, Yunpeng Xie   +10 more
wiley   +1 more source