Results 141 to 150 of about 2,557,215 (346)

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

CLINICAL CASE OF MULTIPLE HEART TUMORS IN NEWBORN

Мать и дитя в Кузбассе, 2019
Heart tumors are a rare pathology, especially in children. They have a varied characteristic. This disease can affect any part of the organ, the pericardium, the myocardium, the valves, the internal tissue of the heart, as well as the septum between the ...
Елена Викторовна Гольцман, Ольга Викторовна Полонская, Ольга Владиславовна Кучма, Дмитрий Александрович Маисеенко, Марина Юрьевна Галактионова   +4 more
doaj  

The role of Nitric oxide and Natriuretic peptide in Heart Failure

, 2023
During this article, natriuretic peptides, which are triggered in heart failure, are also mentioned along with its critical role in cardioprotection.
Phan Nguyen, Bao Tran
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Factors Affecting the Segmentation of the Heart Ventricles in Short Axis Cardiac Perfusion MRI Images

, 2016
Cardiovascular diseases (CVDs) cause 31% of the death rate globally. Automatic accurate segmentation is needed for CVDs early detection. In this paper, we study the effect of the registration and initialization of the level set segmentation on the ...
Doaa Mousa, Inas A. Yassine, Nourhan Zayed   +2 more
core   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Staged repair of borderline hypoplastic heart disease with early biventricular conversionCentral MessagePerspective

JTCVS Techniques
Objective: In select patients with borderline ventricular hypoplasia, we adopted a strategy of initial single-ventricle palliation followed by staged or direct biventricular conversion by 2 years of age.
Nicholas D. Andersen, MD, Douglas M. Overbey, MD, Neel K. Prabhu, MD, Andrew W. McCrary, MD, MSc, Jennifer I. Sherwin, MD, Veerajalandhar Allareddy, MD, Joseph W. Turek, MD, PhD   +6 more
doaj   +1 more source

CaMKII is activated in ventricles of hearts following transverse aortic banding.

, 2016
A) Representative western blots of phosphorylated CaMKII (P-CaMKII), oxidized CaMKII (Ox-CaMKII), total CaMKII (T-CaMKII) and GAPDH in ventricles of sham and TAB mice as labelled by whole-heart biotinylation.
Zhiyong Zhu (2559349), Ana Sierra (623502), Mark E. Anderson (13589), Siva Rama Krishna Koganti (2559343), Denice M. Hodgson-Zingman (2559352), Ankit Maheshwari (2559346), Zhan Gao (271239), Leonid V. Zingman (2559337), Ekaterina Subbotina (2559340)   +8 more
core   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Studies in complete heart-block in man, with special reference to the action of drugs on the rate of the ventricles [PDF]

, 1933
In the following pages an attempt is made to discuss certain aspects of complete heart-block as it occurs in man. While the nervous control of the auricles is well understood, much remains to be discovered regarding the influence of the extrinsic ...
Gilchrist, A. Rae
core