Results 151 to 160 of about 2,557,215 (346)
The pulmonary component of the second heart sound in acquired aortic stenosis.
, 1981 The amplitude of the pulmonic component of the second sound in aortic stenosis was studied in 49 patients with this lesion. As controls, 50 normal subjects were also studied.
A. A. Luisada +9 more
core +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Prioritization of management strategies in patients with normotensive acute pulmonary embolism is based on the identification of individuals at risk for early deterioration.
Yizhuo Gao +9 more
doaj +1 more source
Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
Advanced Science, EarlyView.This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Soft and Adhesive Cardiac Patch for Electrophysiological and Contraction Measurement
Advanced Science, EarlyView.This study developed an epicardial electronic patch with a modulus similar to that of the heart (approximately 65kPa), which can collect stable electrocardiogram signals and myocardial contractility on the surface of a dynamically beating heart. This is attributed to the hydrogen bond interaction formed between the amino and catechol groups in the ...
Wuliang Chen +10 more
wiley +1 more source
Synchronization‐Dissipation in the Cardiorespiratory System
Advanced Science, EarlyView.By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border +3 more
wiley +1 more source
Advanced Science, EarlyView.A mechanically interlocked polyrotaxane hydrogel integrates sliding macrocycles within a covalent network, yielding skin‑like softness, high stretchability, robust adhesion, and stable ionic conductivity. This multifunctional interface enables simultaneous high‑fidelity monitoring of human motion and epidermal electrophysiological signals (ECG/EMG ...
Hao‐Zheng Huang +9 more
wiley +1 more source
A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells
Advanced Science, EarlyView.A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong +13 more
wiley +1 more source
Advanced Science, EarlyView.This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song +10 more
wiley +1 more source