The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng +7 more
wiley +1 more source
In vivo single-cell RNA metabolic labeling resolves early transcriptional responders in the regenerating zebrafish heart. [PDF]
Mintcheva J +16 more
europepmc +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
A Benign Outpouching Masquerading as a Scar: A Case of an Incidentally Diagnosed Cardiac Diverticulum. [PDF]
Tabibiazar R, Daneshvar S.
europepmc +1 more source
ABSTRACT Limited access to cadavers necessitates the availability of digital resources for anatomy education. Smartphone‐based photogrammetry offers a promising solution for creating three‐dimensional (3D) and augmented reality (AR) models. This study compared two mobile photogrammetry applications (Qlone and Polycam) that have been used in modern ...
Sarita Phukwantong +3 more
wiley +1 more source
Beyond the right ventricle: left heart involvement in pulmonary arterial hypertension. [PDF]
Cabada-García MJ +16 more
europepmc +1 more source
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová +11 more
wiley +1 more source
Strain Analysis from Transverse CMR Cine Imaging in Congenital Heart Disease: Feasibility, Reproducibility, and Comparison to Global Longitudinal Strain. [PDF]
Zieschang V +10 more
europepmc +1 more source
Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model
ABSTRACT Background Novel stent technologies offer early intravascular treatment options for coarctation (COA). Mid‐to‐long‐term cardiovascular responses to early COA stent interventions are undefined. Aims We studied a porcine model of COA, with and without early stent implantation with serial dilation to adult aortic diameters, aiming to define ...
Leah M. Gober +7 more
wiley +1 more source
Original investigation: evolution of long-term cardiac tumours in patients with tuberous sclerosis. [PDF]
Santorio NC +8 more
europepmc +1 more source

