Results 171 to 180 of about 1,479,141 (292)

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Aortic Atresia With Ventricular Septal Defect and Normal-Sized Left Ventricle Mimicking Truncus Arteriosus. [PDF]

Case Rep Cardiol
Ho CL, Chow PC.
europepmc   +1 more source

Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen, Julia Riedesel, Juliane Stein, Brandon H. Greene, Svenja Rohde, Sonja Suess, Bjoern Keiner, Priya Panjwani, Padmapriya Ponnuswamy, Juan E. Camacho Londoño   +9 more
wiley   +1 more source

Genome‐wide network analysis identifies the lncRNA‐92467/miR‐205‐5p/PTPRM/CAMs axis in a rat model of hypoxic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen, Yi‐Bing Chen, Xin Li, Xiang Xu, Ge Guo, Han‐Lu Li, Yong‐Ming Yao, Chun‐Lei Liu   +7 more
wiley   +1 more source

One Ventricle, 3000 Proteins: Unraveling the Molecular Landscape of the Fontan Circulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Jennifer P. Woo, Alexander R. Opotowsky
doaj   +1 more source

Ventricle-Specific Biomechanical Responses to Inotropic and Vasoactive Drugs in Human Myocardial Slices. [PDF]

J Cardiovasc Transl Res
Langmuur SJJ, Amesz JH, Alipour Symakani RS, Veen KM, Meuwese CL, Bogers AJJC, de Groot NMS, Manintveld OC, Taverne YJHJ.   +8 more
europepmc   +1 more source

Case of Rupture of the Right Ventricle of the Heart [PDF]

BMJ
openaire   +2 more sources

Ulcer of the stomach, opening into the left ventricle of the heart [PDF]

Transactions of the Royal Academy of Medicine in Ireland, 1886
openaire   +2 more sources

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

In silico optimization of regenerative cell therapy in the infarcted human ventricles to mitigate arrhythmic burden. [PDF]

Stem Cell Reports
Riebel LL, Wang ZJ, Zhou X, Berg LA, Trovato C, Rodriguez B.   +5 more
europepmc   +1 more source