Cardiac Impulse Propagation: An Integrated View. [PDF]
JACC Basic Transl SciQu Z, Shivkumar K.
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The Anatomical Record, EarlyView.Abstract The heart is the central organ of the cardiovascular system. The myocardium is composed of a three‐dimensional network of fibers arranged in clockwise and counterclockwise helices, which are essential for proper cardiac contraction. This study aimed to describe the stratigraphic and morpho‐functional pattern of the porcine myocardium to ...
Mauricio Oliveira da Silva +3 more
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Leonardo di ser piero da Vinci-a bridge between ancient and post-Galenic anatomy based on studies of the ventricular system of the brain. [PDF]
Front NeuroanatDzierżanowski J +4 more
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Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
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Endocardial TIE2 orchestrates cardiac trabeculation via sequestering FOXO1 within the cytoplasm and stimulating versican cleavage. [PDF]
DevelopmentBaldwin HS +5 more
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Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis
Arthritis &Rheumatology, EarlyView.Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo +7 more
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Assessing the importance of sex and disease-specific anatomy in electrophysiology and mechanical simulations with a newly developed public virtual cohort of four-chamber heart models. [PDF]
PLoS Comput BiolSolís-Lemus JA +16 more
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Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart
Arthritis &Rheumatology, EarlyView.Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald +9 more
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A Retrospective Analysis of Cardiac Anatomy in Patients Undergoing the Fontan Operation. [PDF]
CureusTalwar S, Sarkar S, Gupta S, Bhende VV.
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British Journal of Clinical Pharmacology, EarlyView.SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić +7 more
wiley +1 more source