Results 201 to 210 of about 129,264 (305)

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Characterization of a deformable beating cardiac phantom with real-time dosimetric capabilities for validation of MRI-guided heart radiotherapy. [PDF]

Med Phys
Aubert MMN, Uijtewaal P, Penev KI, LeChasseur Y, Hartman N, de Vries LJM, Tzitzimpasis P, Borman PTS, Mandija S, Fast MF, van Lier ALHMW.   +10 more
europepmc   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Male with chest pain after blunt trauma. [PDF]

J Am Coll Emerg Physicians Open
Nix K, DiMeo N, Stults G, Daniel L, Baker J.   +4 more
europepmc   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

Animal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen, Xijia Shao, Xiulin Zhang, Ningning Zhang, Xiao Chen, Guangxin Yue, Jiangping Song   +6 more
wiley   +1 more source

Natural Shear Wave Elastography: A Promising Tool to Assess Myocardial Stiffness in Fontan Patients. [PDF]

JACC Adv
Cattapan I, Youssef A, Cieplucha A, Van Belle H, Caenen A, Salaets T, Orlowska M, Castaldi B, Di Salvo G, Cools B, Budts W, Gewillig M, D'hooge J, Voigt JU, Van De Bruaene A.   +14 more
europepmc   +1 more source

The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart

Animal Models and Experimental Medicine, EarlyView.
The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang, Haifeng Jiang, Zhen Xu, Tingyu Dong, Xiaoyi Liu, Shangxue Yan, Jiajie Kuai, Yan Chang, Wei Wei   +8 more
wiley   +1 more source

Sodium Channel Isoform Diversity Underlies Chamber-Specific Cardiac Excitability. [PDF]

Circ Res
Clark CJ, Anderson CE, Dou A, Dierdorff JM, Galpin JD, Gissot L, Thompson SG, Choi H, Yoon JY, Infield DT, McLendon JM, Hoeger JM, Rabab'h O, Bronk P, Leeds K, Kutschke WJ, Paradee WJ, Boudreau RL, Choi BR, London B, Ahern CA.   +20 more
europepmc   +1 more source

Interpreting the ECG of a Patient with a Pacemaker [PDF]

, 2011
Ginter, James F, Loftis, Patrick
core   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source