Heart Failure in Humans Reduces Contractile Force in Myocardium from Both Ventricles [PDF]
This study measured how heart failure affects the contractile properties of the human myocardium from the left and right ventricles. The data showed that maximum force and maximum power were reduced by approximately 30% in multicellular preparations from
Biesiadecki, Brandon J+6 more
core +1 more source
Adversarial Convolutional Networks with Weak Domain-Transfer for Multi-sequence Cardiac MR Images Segmentation [PDF]
Analysis and modeling of the ventricles and myocardium are important in the diagnostic and treatment of heart diseases. Manual delineation of those tissues in cardiac MR (CMR) scans is laborious and time-consuming.
C Petitjean+6 more
core +3 more sources
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu+6 more
wiley +1 more source
A piece of hammer in the right ventricle of the heart
A 29-year-old male was referred to the surgery department with face injury after being hit with a small hammer fragment at work. Upon admission, he was slightly bleeding from the lacerated wound (size of 1×1 cm) in the maxillofacial region. Radiograph of the skull detected a small dense fragment in the region of injury (fig 1) and the patient was ...
Petr Widimsky+5 more
openaire +4 more sources
Echocardiographic recognition of a criss-cross heart with double outlet right ventricle [PDF]
Crisscross heart (CCH) is a rare cardiac malformation characterized by crossing of the inflow streams of the two ventricles due to an apparent twisting of the heart about its long axis.
Taksande, Amar M.
core +1 more source
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García+23 more
wiley +1 more source
Importance of the right ventricle in valvular heart disease [PDF]
The importance of the right ventricle as a determinant of clinical symptoms, exercise capacity, peri-operative survival and postoperative outcome has been underestimated for a long time. Right ventricular ejection fraction has been used as a measure of right ventricular function but has been found to be dependent on loading conditions, ventricular ...
Nagel, E, Stuber, M, Hess, O M
openaire +5 more sources
Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song+6 more
wiley +1 more source
Development of the heart: (2) Septation of the atriums and ventricles [PDF]
In the first part of our review of cardiac development,1 we discussed the initial changes involved in transformation of the heart forming regions of the embryo into the great veins, the atrial and ventricular chambers, and the arterial trunks. We showed that this first part of cardiac development could be divided into phases of formation of the primary
Robert H. Anderson+4 more
openaire +5 more sources
Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts [PDF]
Objectives: The function of Kv4.3 (KCND3) channels, which underlie the transient outward current I,, in human heart, can be modulated by several accessory subunits such as KChIP2 and KCNE1-KCNE5.
Banse, U.+8 more
core +1 more source