Results 51 to 60 of about 2,557,215 (346)

The Right Ventricle in Congenital Heart Diseases

, 2021
Right ventricular function is an important determinant of prognosis and outcome in congenital heart diseases. Right ventricular (RV) adaptation to congenital heart diseases (CHD) has many faces as there is a wide variety in defects involving the right ventricle as well as in treatment strategies.
Bartelds, Beatrijs, Douwes, Johannes Menno, Berger, Rolf M. F.   +2 more
openaire   +2 more sources

3D bioprinting of collagen to rebuild components of the human heart

Science, 2019
If I only had a heart 3D bioprinting is still a fairly new technique that has been limited in terms of resolution and by the materials that can be printed. Lee et al.
Andrew Lee, Andrew R Hudson, Daniel J. Shiwarski, J. Tashman, Thomas Hinton, S. Yerneni, J. Bliley, Phil Campbell, A. Feinberg   +8 more
semanticscholar   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Stereological analysis of heart ventricles during the development of osteoarthritis in Dunkin Hartley Guinea Pigs [PDF]

, 2022
Introduction: Osteoarthritis (OA) was attributed to mobility issues which implicate an increased workload of the heart. This imposed greater stress on the ventricular wall, resulting in a maladaptive reaction known as left ventricular hypertrophy (LVH ...
Md Yusof, Nur Azirah, Roseman, Nur Amani Hanis, Rosnan, Siti Hafizah, AKMAN, AKMA AZMIERA, Talib, Nurul Ain Aisyah, Zamli, Zaitunnatakhin   +5 more
core  

Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome

, 2021
Background: Complex molecular programs in specific cell lineages govern human heart development. Hypoplastic left heart syndrome (HLHS) is the most common and severe manifestation within the spectrum of left ventricular outflow tract obstruction defects ...
Northoff, B., Hein, Lutz, Crotti, L., Lahm, Harald, Kupatt, C., Dreßen, Martina, Lahm, H., Doppler, S., Berutti, R., Laugwitz, K., Dendorfer, A., Gruber, Peter J., Sahara, M., Bowles, Neil E., Sudhop, S., Puluca, Nazan, Paige, Sharon, Brade, Thomas, Goedel, Alexander, Sahara, Makoto, Bezzina, C., Mastantuono, E., Dorn, T., Laue, Svenja, Goedel, A., Dorn, Tatjana, Doppler, Stefanie A., Schneider, Pedro, Santamaria, G., Lange, R. diger, Rawat, H., Wu, S., Northoff, Bernd, Bezzina, Connie, Meitinger, T., My, I., Abou-Ajram, Claudia, Zhang, Z., Bowles, N., Doll, S., Brade, T., Rijlaarsdam, Maria E., Laue, S., Dressen, M., Rawat, Hilansi, Cleuziou, J., Krane, M., Gruber, P.J., Gilsbach, R., Laugwitz, Karl-Ludwig, Gelb, B.D., Berutti, Riccardo, Paige, S., My, Ilaria, Krane, Markus, Mann, Matthias, Rijlaarsdam, M., Bezzina, C.R., Schneider, C.M., Holdt, Lesca M., Gelb, B., Zhang, Zhong, Neb, I., Hein, L., Tjong, Fleur V. Y., Abou-Ajram, C., Mann, M., Lang, N., Schneider, P., Puluca, N., Sudhop, Stefanie, Schwarz, S., Wu, Sean, Cleuziou, Julie, Mastantuono, Elisa, Kupatt, Christian, Gilsbach, Ralf, Holdt, L.M., Dendorfer, Andreas, Moretti, A., Doll, Sophia, Sinnecker, D., Neb, Irina, Lang, Nora, Gruber, P., Meitinger, Thomas, Sinnecker, Daniel, Lange, R., Tjong, F.V.Y., Schneider, C., Holdt, L., Tjong, F., Rijlaarsdam, M.E., Gelb, Bruce D., Crotti, Lia, Schwarz, Sascha, Santamaria, Gianluca, Doppler, S.A., Bowles, N.E., Laugwitz, K.L., Schneider, Christine M., Moretti, Alessandra   +101 more
core   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Impact of pulmonary hypertension on biventricular functions tissue doppler echocardiographic study

Egyptian Journal of Chest Disease and Tuberculosis, 2017
Background: Pulmonary hypertension (PH) essentially involves the right heart. Also left ventricular (LV) systolic and diastolic functions may be affected.
Mohamed Mahmoud, Ibrahim M. Shalan, Haitham A. Azeem   +2 more
doaj   +1 more source

Evaluation and Management of the Child and Adult With Fontan Circulation: A Scientific Statement From the American Heart Association.

Circulation, 2019
It has been 50 years since Francis Fontan pioneered the operation that today bears his name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a vast array of congenital cardiac lesions when a circulation with 2 ...
J. Rychik, A. Atz, D. Celermajer, B. Deal, M. Gatzoulis, M. Gewillig, T. Hsia, D. Hsu, A. Kovacs, B. McCrindle, J. Newburger, N. Pike, M. Rodefeld, D. Rosenthal, K. Schumacher, B. Marino, Karen K Stout, G. Veldtman, A. Younoszai, Y. D'udekem   +19 more
semanticscholar   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, Accepted Article.
Objective The objective is to describe and compare demographic, clinical and serological characteristics of systemic sclerosis (SSc) patients according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Canadian Scleroderma Research Group, M. Baron, M.Y. Choi, P. Docherty, P.R. Fortin, M. Fritzler, G. Gyger, S. Hoa, M. Hudson, A. Ikic, N. Jones, H. Kim, N. Khalidi, M. Larché, S. LeClercq, N. Maltez, A. Man, A. Masetto, J. Pope, D. Robinson, E. Sutton, C. Thorne, Sasha Bernatsky, Sabrina Hoa   +33 more
wiley   +1 more source

Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies

Communications Biology
The left and right ventricles of the human heart are functionally and developmentally distinct such that genetic or acquired insults can cause dysfunction in one or both ventricles resulting in heart failure.
Benjamin Hunter, Mengbo Li, Benjamin L. Parker, Yen Chin Koay, Dylan J. Harney, Evangeline Pearson, Jacob Cao, Gavin T. Chen, Oneka Guneratne, Gordon K. Smyth, Mark Larance, John F. O’Sullivan, Sean Lal   +12 more
doaj   +1 more source