Results 51 to 60 of about 42,577 (256)

Radar-Based Non-Contact Continuous Identity Authentication

Remote Sensing, 2020
Non-contact vital signs monitoring using microwave Doppler radar has shown great promise in healthcare applications. Recently, this unobtrusive form of physiological sensing has also been gaining attention for its potential for continuous identity ...
Shekh Md Mahmudul Islam, Olga Borić-Lubecke, Yao Zheng, Victor M. Lubecke   +3 more
doaj   +1 more source

Vital Signal Detection Using Multi-Radar for Reductions in Body Movement Effects

Sensors, 2021
Vital signal detection using multiple radars is proposed to reduce the signal degradation from a subject’s body movement. The phase variation in the transceiving signals of continuous-wave radar due to respiration and heartbeat is generated by the body ...
Ah-Jung Jang, In-Seong Lee, Jong-Ryul Yang   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Respiratory and cardiac interoceptive sensitivity in the first two years of life

eLife
Several recent theoretical accounts have posited that interoception, the perception of internal bodily signals, plays a vital role in early human development. Yet, empirical evidence of cardiac interoceptive sensitivity in infants to date has been mixed.
Markus R Tünte, Stefanie Hoehl, Moritz Wunderwald, Johannes Bullinger, Asena Boyadziheva, Lara Maister, Birgit Elsner, Manos Tsakiris, Ezgi Kayhan   +8 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Wearable Electrospun Nanofibrous Sensors for Health Monitoring

Micro
Various electrospinning techniques can be used to produce nanofiber mats with randomly oriented or aligned nanofibers made of different materials and material mixtures.
Nonsikelelo Sheron Mpofu, Tomasz Blachowicz, Andrea Ehrmann, Guido Ehrmann   +3 more
doaj   +1 more source

Web-Based Wireless Monitoring System on Patient’s Vital Sign [PDF]

E3S Web of Conferences, 2019
Examination of vital signs such as blood pressure, heart rate, and body temperature is the most basic essential function of the body in determining the health status of the patient. In general, examining vital signs performed by a doctor or nurse uses an
Subito Mery, Alamsyah, Amir Ardi
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source