Results 51 to 60 of about 60,130 (290)

Life That Loves to Happen Brochure [PDF]

open access: yes, 1995
Booklet describing and advertising the Heartbeat seminar Life That Loves to Happen.
Heartbeat
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Robust In-Vehicle Heartbeat Detection Using Multimodal Signal Fusion

open access: yes, 2023
Continuous in-vehicle health monitoring enables the earlier detection of diseases. Therefore, we developed a redundant sensor system for heartbeat measurement, which is composed of an electrocardiogram (ECG), and photoplethysmogram (PPG), and a camera ...
Lasenby, Joan   +2 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Radar-Based Non-Contact Continuous Identity Authentication

open access: yesRemote Sensing, 2020
Non-contact vital signs monitoring using microwave Doppler radar has shown great promise in healthcare applications. Recently, this unobtrusive form of physiological sensing has also been gaining attention for its potential for continuous identity ...
Shekh Md Mahmudul Islam   +3 more
doaj   +1 more source

Vital Signal Detection Using Multi-Radar for Reductions in Body Movement Effects

open access: yesSensors, 2021
Vital signal detection using multiple radars is proposed to reduce the signal degradation from a subject’s body movement. The phase variation in the transceiving signals of continuous-wave radar due to respiration and heartbeat is generated by the body ...
Ah-Jung Jang   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Real-Time Evaluation Algorithm for Noncontact Heart Rate Variability Monitoring

open access: yesSensors, 2023
Noncontact vital sign monitoring based on radar has attracted great interest in many fields. Heart Rate Variability (HRV), which measures the fluctuation of heartbeat intervals, has been considered as an important indicator for general health evaluation.
Xiangyu Han   +7 more
doaj   +1 more source

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