Results 61 to 70 of about 145,692 (284)

The Miracle of the Heartbeat

Journal of the Islamic Medical Association of North America, 2011
My fifth pacemaker made me think of the divine miracle of our hearts' function.
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Feature extraction of speech signal and heartbeat detection in angry emotion identification [PDF]

, 2013
Angry is one of emotions that play an essential role in decision making, perception, learning and more. This paper detects the angry emotion by analyzing and recognizing angry speech signal as well as detecting the heartbeat condition.
Ahmad, Ida Laila, Lee, Chee Chuan, Mohamed, Masnani   +2 more
core  

Multifractality in Human Heartbeat Dynamics

, 1999
Recent evidence suggests that physiological signals under healthy conditions may have a fractal temporal structure. We investigate the possibility that time series generated by certain physiological control systems may be members of a special class of ...
A-L Barabasi, C Meneveau, C-K Peng, C-K Peng, C-S Poon, G Sugihara, GB Moody, H Takayasu, HE Hurst, HE Stanley, HE Stanley, I Daubechies, J Lefebvre, JB Bassingthwaighte, JF Muzy, JF Muzy, JK Kanters, JM Hausdorff, LAN Amaral, M Kobayashi, M Malik, MF Shlesinger, PCh Ivanov, PCh Ivanov, S Akselrod, S Thurner, T Vicsek, T Vicsek, TG Dewey, Y Yamamoto   +29 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Radar-Based Non-Contact Continuous Identity Authentication

Remote Sensing, 2020
Non-contact vital signs monitoring using microwave Doppler radar has shown great promise in healthcare applications. Recently, this unobtrusive form of physiological sensing has also been gaining attention for its potential for continuous identity ...
Shekh Md Mahmudul Islam, Olga Borić-Lubecke, Yao Zheng, Victor M. Lubecke   +3 more
doaj   +1 more source

Vital Signal Detection Using Multi-Radar for Reductions in Body Movement Effects

Sensors, 2021
Vital signal detection using multiple radars is proposed to reduce the signal degradation from a subject’s body movement. The phase variation in the transceiving signals of continuous-wave radar due to respiration and heartbeat is generated by the body ...
Ah-Jung Jang, In-Seong Lee, Jong-Ryul Yang   +2 more
doaj   +1 more source

Slow invariant manifold of heartbeat model [PDF]

, 2014
A new approach called Flow Curvature Method has been recently developed in a book entitled Differential Geometry Applied to Dynamical Systems. It consists in considering the trajectory curve, integral of any n-dimensional dynamical system as a curve in ...
Ginoux, Jean-Marc, Rossetto, Bruno
core