Results 41 to 50 of about 18,916 (251)

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman, Maria Yasmine, Dunia Hatabah, Noor Alzraikat, Frank Harris, Lou Ann Brown, Satheesh Chonat, Nitya Bakshi, Chris A. Rees, Carlton Dampier, Claudia R. Morris   +10 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Novel implantation of vagus nerve stimulator AspireSR pulse generator: Technical note

Interdisciplinary Neurosurgery, 2017
Objective: To eliminate the need for preoperative evaluation required for the Aspire SR pulse generator and allow for minimum sensitivity settings, thereby providing the most accurate setting for cardiac-based seizure detection (CBSD).
J. Will Robbins, M.D., Jordan Lacy, M.D., Mark Puccioni, M.D.   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Accurate Heartbeat Detection on Ballistocardiogram Accelerometric Traces

IEEE Transactions on Instrumentation and Measurement, 2020
This article presents an automated procedure for acquisition and analysis of BallistoCardioGraphy (BCG) traces. A triaxial accelerometer and a microcontroller unit are used to record heart-induced recoil forces generated from a lying subject. The problem of BCG J-peak annotation is split into two subtasks: candidates extraction, based on a detection ...
Niccolò Mora, Federico Cocconcelli, Guido Matrella, Paolo Ciampolini   +3 more
openaire   +3 more sources

Non-Contact Detection of Vital Signs Using a UWB Radar Sensor

IEEE Access, 2019
The ultra-wide band (UWB) radar sensor is useful in the field of mission critical sensors and sensor networks due to its short detection time, high penetration, and low energy consumption.
Zhenzhen Duan, Jing Liang
doaj   +1 more source

Optimized Solutions of Electrocardiogram Lead and Segment Selection for Cardiovascular Disease Diagnostics

Bioengineering, 2023
Most of the existing multi-lead electrocardiogram (ECG) detection methods are based on all 12 leads, which undoubtedly results in a large amount of calculation and is not suitable for the application in portable ECG detection systems.
Jiguang Shi, Zhoutong Li, Wenhan Liu, Huaicheng Zhang, Qianxi Guo, Sheng Chang, Hao Wang, Jin He, Qijun Huang   +8 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Detection of Heartbeat Components Through Doppler Radar Systems Using Semantic Segmentation and Non-Harmonic Analysis

IEEE Access
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an increased focus on the routine analysis of vital signs such as breathing and pulse rates. Radar technology has proven effective for non-contact, long-term monitoring
Ryota Goto, Taichi Horimoto, Shotaro Koyama, Tsubasa Suzuki, Junpei Tsutsumi, Taisei Matsuyama, Masaya Hasegawa, Shigeki Hirobayashi, Kazuo Yoshida   +8 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source