Results 51 to 60 of about 18,916 (251)

Dynamic heartbeat detection algorithm based on RBFNN

The Journal of Engineering, 2019
The operational environment faced by modern radars is becoming increasingly complex. The timely detection of the failure of a node and the adoption of countermeasures to ensure the stable operation of the system have become the focus of radar network ...
Xiaoqing Cui, Zhifeng Ma
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A QRS Detection and R Point Recognition Method for Wearable Single-Lead ECG Devices

Sensors, 2017
In the new-generation wearable Electrocardiogram (ECG) system, signal processing with low power consumption is required to transmit data when detecting dangerous rhythms and to record signals when detecting abnormal rhythms.
Chieh-Li Chen, Chun-Te Chuang
doaj   +1 more source

Sex-Specific Relationships Between Interoceptive Accuracy and Emotion Regulation

Frontiers in Behavioral Neuroscience, 2020
Over the last years, there has been a resurge in the interest to study the relationship between interoception and emotion. By now, it is well established that interoception contributes to the experience of emotions.
Alexander Lischke, Rike Pahnke, Anett Mau-Moeller, Anett Mau-Moeller, Robert Jacksteit, Matthias Weippert   +5 more
doaj   +1 more source

Heart Rate Variability Modulates Interoceptive Accuracy

Frontiers in Neuroscience, 2021
Our emotional experiences depend on our interoceptive ability to perceive and interpret changes in our autonomous nervous system. An inaccurate perception and interpretation of autonomic changes impairs our ability to understand and regulate our ...
Alexander Lischke, Rike Pahnke, Anett Mau-Moeller, Matthias Weippert   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

AF-DETR: Transformer-Based Object Detection for Precise Atrial Fibrillation Beat Localization in ECG

Bioengineering
Atrial fibrillation (AF) detection in electrocardiograms (ECG) remains challenging, particularly at the heartbeat level. Traditional deep learning methods typically classify ECG segments as a whole, limiting their ability to detect AF at the granularity ...
Peng Wang, Junxian Song, Pang Wu, Zhenfeng Li, Xianxiang Chen, Lidong Du, Zhen Fang   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Robust Multimodal Heartbeat Detection Using Hybrid Neural Networks

IEEE Access, 2020
Many arrhythmia datasets are multimodal due to the simultaneous collection of physiological signals of a subject. These datasets frequently have missing modalities or missing block-wise data, a characteristic that various recent applications of neural ...
Michael R. Schwob, Aeren Dempsey, Felix Zhan, Justin Zhan, Asif Mehmood   +4 more
doaj   +1 more source