Results 71 to 80 of about 53,782 (273)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Heart Rate Variability Modulates Interoceptive Accuracy
Frontiers in Neuroscience, 2021 Our emotional experiences depend on our interoceptive ability to perceive and interpret changes in our autonomous nervous system. An inaccurate perception and interpretation of autonomic changes impairs our ability to understand and regulate our ...
Alexander Lischke +3 more
doaj +1 more source
Feasibility Testing of the Alert for AFib Intervention. [PDF]
, 2017 Improving early detection and treatment of atrial fibrillation (AF) is critical because untreated AF is a major contributor to stroke and heart failure. We sought to generate knowledge about the feasibility of conducting a randomized controlled trial to ...
Austin, Christine +5 more
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Robust Multimodal Heartbeat Detection Using Hybrid Neural Networks
IEEE Access, 2020 Many arrhythmia datasets are multimodal due to the simultaneous collection of physiological signals of a subject. These datasets frequently have missing modalities or missing block-wise data, a characteristic that various recent applications of neural ...
Michael R. Schwob +4 more
doaj +1 more source
Design Concept for a Failover Mechanism in Distributed SDN Controllers [PDF]
, 2017 Software defined networking allows the separation of the control plane and data plane in networking. It provides scalability, programmability, and centralized control. It will use these traits to reach ubiquitous connectivity.
Kong, Nathan
core +2 more sources
The peculiar 2011 outburst of the black hole candidate IGR J17091-3624, a GRS 1915+105 like source?
, 2012 We report on the long-term monitoring campaign of the black hole candidate IGR J17091-3624 performed with INTEGRAL and Swift during the peculiar outburst started on January 2011.
Bozzo, Enrico +5 more
core +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
H2B: Heartbeat-based Secret Key Generation Using Piezo Vibration Sensors
, 2019 We present Heartbeats-2-Bits (H2B), which is a system for securely pairing wearable devices by generating a shared secret key from the skin vibrations caused by heartbeat. This work is motivated by potential power saving opportunity arising from the fact
Hassan, Mahbub +6 more
core +1 more source