Results 1 to 10 of about 61,846 (265)

Empowering Pharmacists in Heartburn Management: Practical Insights for OTC Treatment and Self-Care [PDF]

Pharmacy
Heartburn is a prevalent and frequently self-managed condition, with a myriad of over-the-counter (OTC) treatment options available for self-care. The potential for misinterpretation of drug labels and improper OTC medication selection may result in ...
Mary Barna Bridgeman, Ashok Hospattankar, Kamran Siddiqui, Nardine Nakhla   +3 more
doaj   +2 more sources

Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn

New England Journal of Medicine, 2019
BACKGROUND Heartburn that persists despite proton-pump inhibitor (PPI) treatment is a frequent clinical problem with multiple potential causes. Treatments for PPI-refractory heartburn are of unproven efficacy and focus on controlling gastroesophageal ...
Robert H Lee, Hiroshi L Mashimo, Vivian M Sanchez   +2 more
exaly   +2 more sources

Health-related quality of life improves with treatment-related GERD symptom resolution after adjusting for baseline severity [PDF]

Health and Quality of Life Outcomes, 2003
Severity and frequency of gastroesophageal reflux disease (GERD) related symptoms are associated with impaired health-related quality of life (HRQL). This study evaluated the association between baseline heartburn severity and endpoint HRQL of patients ...
Joshua-Gotlib Sandra, Zodet Marc W, Revicki Dennis A, Levine Douglas, Crawley Joseph A   +4 more
doaj   +2 more sources

Radiofrequency ablation reduces esophageal hypersensitivity in refractory non-erosive reflux disease [PDF]

Frontiers in Medicine
Refractory non-erosive gastroesophageal reflux disease (rNERD) involves complex interactions between esophageal sensitivity receptors (PAR2/TRPV1) and persistent proton pump inhibitor (PPI)-refractory symptoms.
Yan Chen, Yan Chen, Xin Lu, Xin Lu, Ming Cheng, Ming Cheng, Mingrui Cui, Mingrui Cui, Xuejun Wen, Xuejun Wen, Kai Mu, Ping Wang, Ying-Jian Zhang, Ying-Jian Zhang   +13 more
doaj   +2 more sources

The prevalence and risk factors of gastroesophageal reflux disease among medical students in southwestern Saudi Arabia [PDF]

Journal of Family Medicine and Primary Care
Background: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal disorders. Medical students experience unique dietary and lifestyle changes due to their demanding coursework and stressful examinations.
Abdullah A. Al-Shahrani, Reem T. Alalyani, Abdulaziz A. Al Hatem, Lubna M. Ladnah, Mohammed M. Alshahrani, Ibrahim Tawhari, Mohammed A. Alzahrani   +6 more
doaj   +2 more sources

Tegoprazan in Gastroesophageal Reflux Disease and Related Acid‐Mediated Conditions: A Systematic Review and Meta‐Analysis [PDF]

JGH Open
Gastroesophageal reflux disease (GERD) is a chronic relapsing disorder often inadequately controlled with proton pump inhibitors (PPIs), particularly in patients with nocturnal acid breakthrough (NAB) or non‐erosive reflux disease (NERD).
Sanjay Bandyopadhyay, Mahesh Goenka, Debapratim Routh, G. N. Ramesh, Parimal Lawate   +4 more
doaj   +2 more sources

Inconsistency in the Diagnosis of Functional Heartburn: Usefulness of Prolonged Wireless pH Monitoring in Patients With Proton Pump Inhibitor Refractory Gastroesophageal Reflux Disease [PDF]

Journal of Neurogastroenterology and Motility, 2015
Background/Aims The diagnosis of functional heartburn is important for management, however it stands on fragile pH monitoring variables, ie, acid exposure time varies from day to day and symptoms are often few or absent.
Domingues, G, Mauro, A, Penagini, R, Sifrim, D, Sweis, R, Vales, A   +5 more
core   +2 more sources

Exploratory analyses of meal‐induced heartburn identify distinct clinical phenotypes of gastroesophageal reflux disease [PDF]

Physiological Reports
Symptoms in symptomatic GERD patients result from esophageal acid exposure and are treated with agents that inhibit gastric acid secretion. We analyzed data from a clinical trial evaluating the effect of ranitidine plus antacid on heartburn severity in ...
Jerry D. Gardner, George Triadafilopoulos   +1 more
doaj   +2 more sources

Fermented soy supplementation improves indicators of quality of life: a randomized, placebo-controlled, double-blind trial in adults experiencing heartburn

BMC Research Notes, 2020
Objective To determine if fermented soy supplementation relieves heartburn and improves gastrointestinal symptoms and quality of life, a randomized, double-blind parallel study was conducted with adults experiencing mild or moderate heartburn ...
Asmaa Fatani, Kadi Vaher, Daniela Rivero-Mendoza, Karima Alabasi, Wendy J. Dahl   +4 more
doaj   +2 more sources

Esophageal Epithelial-Derived IL-33 Is Upregulated in Patients with Heartburn. [PDF]

PLoS ONE, 2016
Interleukin-33 (IL-33) is a tissue-derived cytokine that is constitutively expressed in epithelial cells of tissues exposed to the environment and plays a role in sensing damage caused by inflammatory diseases.
Hiroo Sei, Tadayuki Oshima, Jing Shan, Liping Wu, Takahisa Yamasaki, Takuya Okugawa, Takashi Kondo, Toshihiko Tomita, Hirokazu Fukui, Jiro Watari, Hiroto Miwa   +10 more
doaj   +2 more sources