Results 101 to 110 of about 24,539 (235)

Visual Findings and Reported Symptoms Do Not Correlate With Laryngopharyngeal Reflux, Underscoring the Need for Confirmatory Diagnostics

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objective To assess the correlation between hypopharyngeal acid exposure, symptom questionnaires, and pharyngeal findings in patients with suspected laryngopharyngeal reflux (LPR) and to provide normative data for hypopharyngeal acid reflux in healthy Finnish subjects.
Markku Patjas, Anthony Maalouf, Pia Järvenpää, Timo Mustonen, Teemu Kinnari, Ahmed Geneid   +5 more
wiley   +1 more source

Twenty‐Four Month Outcomes From a Real‐World Telehealth Obesity Treatment Clinic Using Obesity Medications

Obesity, Volume 34, Issue S1, Page 134-143, June 2026.
ABSTRACT Objective Antiobesity medications (AOMs) are indicated for long‐term use; however, evidence of their real‐world long‐term efficacy is limited. This study describes clinical outcomes from 18‐ and 24‐month use of AOMs in a telemedicine weight management clinic.
Kathleen R. Ruddiman, Young‐Rock Hong, Jamy Ard, Rebecca Jones, Adam Medcalf, Gary D. Foster, Jamil Alkhaddo, Michelle Cardel   +7 more
wiley   +1 more source

Efficacy of Plant‐Derived Therapies for Primary Dysmenorrhea: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Phytotherapy Research, Volume 40, Issue 6, Page 3818-3839, June 2026.
ABSTRACT Primary dysmenorrhea is defined as recurrent, cramp‐like lower abdominal pain occurring during menstruation in the absence of underlying pelvic pathology. A significant proportion of the population opts for natural plant‐based remedies due to their perceived lower incidence of adverse effects.
Lifei Wu, Inmaculada Xu Lou, Zhenting Hu, Gan Wang, Sammit Vishram Deshpande, Rocío Cáceres‐Matos   +5 more
wiley   +1 more source

Gabra6 Genetic Polymorphism Is Associated with the Risk of Functional Heartburn in Chinese

, 2009
Background and Aim: Polymorphisms of GABA(A) alpha 6 (GABRA6 )-1521 and IL-1 beta-511 have been linked with susceptibility to stress and gastric acid secretion.
LEE, YI-CHIA;WANG, HSIU-PO;CHIU, HAN-MO;HUANG, SHIH-PEI;LIAO, SHIH-CHENG;CHEN, MING-FONG;LIN, JAW-TOWN;WU, MING-SHIANG, 李宜家;王秀伯;邱瀚模;黃世貝;廖士程;陳明豐;林肇堂;吳明賢   +1 more
core   +1 more source

Prevalence and Predisposing Factors of Helicobacter pylori Infection in Symptomatic Patients: A Multicenter Study in Ghana's Upper East Region

Public Health Challenges, Volume 5, Issue 2, June 2026.
A high Helicobacter pylori prevalence of 65.8% was detected among dyspeptic patients in northern Ghana, linked to poor sanitation, use of public toilets, consumption of street‐vended food, and drinking untreated water. These findings underscore the need for targeted public‐health interventions. ABSTRACT Background Helicobacter pylori (H.
Elvis Ramsy Awuni, Maxwell Akonde, Benedict Boateng Antuamwine   +2 more
wiley   +1 more source

Validation of a Four-Graded Scale for Severity of Heartburn in Patients with Symptoms of Gastroesophageal Reflux Disease

, 2008
ObjectivesTo evaluate the reliability, responsiveness, and validity of a four-graded symptom severity scale (none, mild, moderate, severe) and an eight-graded frequency scale (number of days with symptoms during past week) for assessment of heartburn ...
Ingela Wiklund, Junghard, Ola, Ola Junghard, Wiklund, Ingela   +3 more
core   +1 more source

Clinical, Dietary, Lifestyle and Genetic Factors Associated With Age at Onset of Esophageal Adenocarcinoma

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background Esophageal adenocarcinoma (EAC) represents one of the most increasing malignancies in Western countries. The disease is multifactorial, involving modifiable risk factors and genetic susceptibility variants. These variants can be aggregated to a polygenic risk score (PRS) that reflects individual genetic risk.
Vera Koch, Ines Gockel, Julian Reingruber, Nicole Kreuser, Jessica Bigge, Marino Venerito, Hakan Alakus, Andrea May, Christian Gerges, René Thieme, Dominik Heider, Axel M. Hillmer, Alanna Ebigbo, Christiane J. Bruns, Hauke Lang, Helmut Messmann, Thomas Rösch, Thaddäus T. Wissniowski, Michaela Müller, Ulrike W. Denzer, Markus M. Nöthen, Michael Vieth, Aaron P. Thrift, Carlo Maj, Johannes Schumacher   +24 more
wiley   +1 more source

Esophageal chest pain resembles heartburn in reflux metrics and response to proton pump inhibitor therapy

Background: Gastro-esophageal reflux disease (GERD) is the most common cause for noncardiac chest pain (NCCP), with an estimated prevalence rate ranging between 30% and 60%. Heartburn and NCCP may share common mechanisms.
Mentore Ribolsi, Lorenzo Marchetti, Savarino Edoardo, Lucrezia Maria Olmi, Michele Cicala   +4 more
core   +1 more source

Randomized controlled trial of intravenous dexamethasone to prevent relapse in the treatment of migraine in a pediatric emergency department

Headache: The Journal of Head and Face Pain, Volume 66, Issue 6, Page 1235-1243, June 2026.
Abstract Objective This study aimed to evaluate whether a single dose of intravenous dexamethasone, when added to standard abortive therapy, reduces relapse of migraine after emergency department (ED) discharge in children and adolescents. Background Migraine is a leading cause of headache presentations to the ED for children and adolescents.
Geneviève Tourigny‐Ruel, Benoit Bailey, Sabrina Jean‐Charles, Jocelyn Gravel   +3 more
wiley   +1 more source

Pathophysiological characteristics of patients with non-erosive reflux disease differ from those of patients with functional heartburn.

, 2004
Background: Patients with endoscopy-negative heartburn can be subdivided into non-erosive reflux disease and functional heartburn on the basis of abnormal and normal, respectively, oesophageal acid exposure.
Frazzoni M, SAVARINO, VINCENZO, De Micheli E, ZENTILIN, PATRIZIA   +3 more
core   +1 more source